Possible mechanism of quadriceps femoris weakness in patients with ruptured anterior cruciate ligament

Yu Konishi, Toru Fukubayashi, Daisuke Takeshita

Research output: Contribution to journalArticle

75 Citations (Scopus)

Abstract

Purpose: The purpose of this study was to test the hypothesis that loss of afferent feedback due to rupture of anterior cruciate ligament (ACL) is the cause of quadriceps femoris (QF) weakness through gamma loop. Two experiments were designed to prove our hypothesis. Methods: In experiment 1, the maximal voluntary contraction (MVC) of knee extension and integrated electromyogram (I-EMG) of vastus medialis (VM), vastus lateralis (VL), and rectus femoris (RF) were measured in 13 patients with ruptured ACL and 7 healthy volunteers before and after injection of anesthetic agent into the knee. In experiment 2, MVC of knee extension and I-EMG of the VM, VL, and RF were measured in 13 patients with ruptured ACL, 7 knee-anesthetized healthy subjects, and 12 normal subjects, before and after 20-min vibration stimulation applied to the infrapatellar tendon. Results: The results of experiment 1 revealed that injection of anesthetic agent into the knee capsule resulted in significant decrease of MVC and I-EMGs. In experiment 2, the mean percentage change of MVC in the control group was significantly lower than that in the other two groups. There was no significant difference between knee-anesthetized group and patients with ruptured ACL. The mean percentage change of I-EMG showed a pattern similar to that of MVC. Conclusion: Our results suggest that loss of feedback from mechanoreceptors in ACL is the underlying mechanism of weakness of QF in patients with ACL lesion. This conclusion is based on chronic suppression of recruitment of high-threshold motor units during voluntary contraction because ACL lesion leads to chronic reduction in Ia-feedback to muscles around the knee due to a lack of feedback from ACL to gamma motor neurons.

Original languageEnglish
Pages (from-to)1414-1418
Number of pages5
JournalMedicine and Science in Sports and Exercise
Volume34
Issue number9
Publication statusPublished - 2002 Sep
Externally publishedYes

Fingerprint

Anterior Cruciate Ligament
Quadriceps Muscle
Knee
Electromyography
Anesthetics
Gamma Motor Neurons
Healthy Volunteers
Mechanoreceptors
Injections
Vibration
Tendons
Capsules
Rupture
Muscles
Control Groups

Keywords

  • ACL injury
  • EMG
  • Reflex inhibition
  • Vibration stimulation

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Physical Therapy, Sports Therapy and Rehabilitation
  • Orthopedics and Sports Medicine

Cite this

Possible mechanism of quadriceps femoris weakness in patients with ruptured anterior cruciate ligament. / Konishi, Yu; Fukubayashi, Toru; Takeshita, Daisuke.

In: Medicine and Science in Sports and Exercise, Vol. 34, No. 9, 09.2002, p. 1414-1418.

Research output: Contribution to journalArticle

Konishi, Yu ; Fukubayashi, Toru ; Takeshita, Daisuke. / Possible mechanism of quadriceps femoris weakness in patients with ruptured anterior cruciate ligament. In: Medicine and Science in Sports and Exercise. 2002 ; Vol. 34, No. 9. pp. 1414-1418.
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