A simple and convenient method for hydroheteroarylation of alkynes using air- stable catalyst precursors is described. The addition of a solution of AlMe3 in hexane to Ni(acac)2 and tri(cyclopentyl)phosphonium tetrafluoroborate ([Cyp3PH\BF4) rapidly generates an active Ni(0)/Cyp3P catalyst for cis-hydroheteroarylation of alkynes under mild conditions. The catalytic reaction is applicable to a wide range of heteroarenes to give heteroaryl-substituted ethenes in excellent stereo- and regioselectivities.
|Number of pages||4|
|Publication status||Published - 2007 Apr 13|
ASJC Scopus subject areas
- Analytical Chemistry
- Organic Chemistry