TY - JOUR
T1 - Precision imaging of 4.4 MeV gamma rays using a 3-D position sensitive Compton camera
AU - Koide, Ayako
AU - Kataoka, Jun
AU - Masuda, Takamitsu
AU - Mochizuki, Saku
AU - Taya, Takanori
AU - Sueoka, Koki
AU - Tagawa, Leo
AU - Fujieda, Kazuya
AU - Maruhashi, Takuya
AU - Kurihara, Takuya
AU - Inaniwa, Taku
N1 - Funding Information:
This research was supported by JSPS KAKENHI Grant Number JP15H05720. Careful supports by technical staffs in the cyclotron facility in NIRS is also acknowledged to complete the experiments presented in the paper.
Publisher Copyright:
© 2018 The Author(s).
PY - 2018/12/1
Y1 - 2018/12/1
N2 - Imaging of nuclear gamma-ray lines in the 1-10 MeV range is far from being established in both medical and physical applications. In proton therapy, 4.4 MeV gamma rays are emitted from the excited nucleus of either 12C∗or 11B∗and are considered good indicators of dose delivery and/or range verification. Further, in gamma-ray astronomy, 4.4 MeV gamma rays are produced by cosmic ray interactions in the interstellar medium, and can thus be used to probe nucleothynthesis in the universe. In this paper, we present a high-precision image of 4.4 MeV gamma rays taken by newly developed 3-D position sensitive Compton camera (3D-PSCC). To mimic the situation in proton therapy, we first irradiated water, PMMA and Ca(OH)2 with a 70 MeV proton beam, then we identified various nuclear lines with the HPGe detector. The 4.4 MeV gamma rays constitute a broad peak, including single and double escape peaks. Thus, by setting an energy window of 3D-PSCC from 3 to 5 MeV, we show that a gamma ray image sharply concentrates near the Bragg peak, as expected from the minimum energy threshold and sharp peak profile in the cross section of 12C(p,p)12C∗.
AB - Imaging of nuclear gamma-ray lines in the 1-10 MeV range is far from being established in both medical and physical applications. In proton therapy, 4.4 MeV gamma rays are emitted from the excited nucleus of either 12C∗or 11B∗and are considered good indicators of dose delivery and/or range verification. Further, in gamma-ray astronomy, 4.4 MeV gamma rays are produced by cosmic ray interactions in the interstellar medium, and can thus be used to probe nucleothynthesis in the universe. In this paper, we present a high-precision image of 4.4 MeV gamma rays taken by newly developed 3-D position sensitive Compton camera (3D-PSCC). To mimic the situation in proton therapy, we first irradiated water, PMMA and Ca(OH)2 with a 70 MeV proton beam, then we identified various nuclear lines with the HPGe detector. The 4.4 MeV gamma rays constitute a broad peak, including single and double escape peaks. Thus, by setting an energy window of 3D-PSCC from 3 to 5 MeV, we show that a gamma ray image sharply concentrates near the Bragg peak, as expected from the minimum energy threshold and sharp peak profile in the cross section of 12C(p,p)12C∗.
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U2 - 10.1038/s41598-018-26591-2
DO - 10.1038/s41598-018-26591-2
M3 - Article
C2 - 29802312
AN - SCOPUS:85047518457
SN - 2045-2322
VL - 8
JO - Scientific Reports
JF - Scientific Reports
IS - 1
M1 - 8116
ER -