Predictive Factors for Oral Intake Recovery After Acute Stroke: Analysis of a Japanese Nationwide Inpatient Database

Yasuhiro Inooka, Hayato Yamana, Yusuke Shinoda*, Haruhi Inokuchi, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga, Nobuhiko Haga

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Objective: It remains unclear which factors contribute to dysphagia recovery after an acute stroke. This study aimed to identify factors associated with complete oral intake recovery in patients with post-stroke dysphagia. Methods: Data were obtained from the Diagnosis Procedure Combination database, which is a nationwide database of administrative claims and discharge abstracts in Japan. We selected patients admitted within 3 days of stroke onset and conducted multivariable logistic regression analysis. Total oral intake within 30 days of admission was the primary outcome measure. Results: A total of 151,302 patients were included, and total oral intake was observed in 48% of them within 30 days of admission. Total oral intake was significantly associated with age, sex, stroke subtype, consciousness disturbance, low body mass index, multiple comorbidities, and the modified Rankin Scale before stroke onset. In addition, males had worse outcomes than females (odds ratio, 0.75; 95% confidence interval, 0.73–0.77, p < 0.001), and intracerebral and subarachnoid hemorrhagic stroke subtypes were associated with non-recovery. Conclusion: This study identified several prognostic factors for total oral intake in patients with acute stroke. These results may be useful for predicting a patient’s dysphagia prognosis at the time of admission and designing a nutritional management plan for patients with acute stroke.

Original languageEnglish
Publication statusAccepted/In press - 2022
Externally publishedYes


  • Acute stroke
  • Dysphagia
  • Oral intake
  • Predictive factors

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Gastroenterology
  • Speech and Hearing


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