Preparation and biological evaluation of hydroxyapatite-coated nickel-free high-nitrogen stainless steel

Makoto Sasaki; Motoki Inoue; Yasuyuki Katada; Yuuki Nishida; Akiyoshi Taniguchi; Sachiko Hiromoto; Tetsushi Taguchi

doi:10.1088/1468-6996/13/6/064213

Preparation and biological evaluation of hydroxyapatite-coated nickel-free high-nitrogen stainless steel

Makoto Sasaki^*, Motoki Inoue, Yasuyuki Katada, Yuuki Nishida, Akiyoshi Taniguchi, Sachiko Hiromoto, Tetsushi Taguchi

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Calcium phosphate was formed on nickel-free high-nitrogen stainless steel (HNS) by chemical solution deposition. The calcium phosphate deposition was enhanced by glutamic acid covalently immobilized on the surface of HNS with trisuccinimidyl citrate as a linker. X-ray diffraction patterns and Fourier transform infrared spectra showed that the material deposited on glutamic acid-immobilized HNS within 24 h was low-crystallinity calcium-deficient carbonate-containing hydroxyapatite (HAp). The biological activity of the resulting HAp-coated HNS was investigated by using a human osteoblast-like MG-63 cell culture. The HAp-coated HNS stimulated the alkaline-phosphate activity of the MG-63 culture after 7 days. Therefore, HAp-coated HNS is suitable for orthopedic devices and soft tissue adhesion materials.

Original language	English
Article number	064213
Journal	Science and Technology of Advanced Materials
Volume	13
Issue number	6
DOIs	https://doi.org/10.1088/1468-6996/13/6/064213
Publication status	Published - 2012 Dec
Externally published	Yes

Keywords

chemical solution deposition
hydroxyapatite
nickel-free high-nitrogen stainless steel
surface modification

ASJC Scopus subject areas

Materials Science(all)

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10.1088/1468-6996/13/6/064213

Cite this

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title = "Preparation and biological evaluation of hydroxyapatite-coated nickel-free high-nitrogen stainless steel",

abstract = "Calcium phosphate was formed on nickel-free high-nitrogen stainless steel (HNS) by chemical solution deposition. The calcium phosphate deposition was enhanced by glutamic acid covalently immobilized on the surface of HNS with trisuccinimidyl citrate as a linker. X-ray diffraction patterns and Fourier transform infrared spectra showed that the material deposited on glutamic acid-immobilized HNS within 24 h was low-crystallinity calcium-deficient carbonate-containing hydroxyapatite (HAp). The biological activity of the resulting HAp-coated HNS was investigated by using a human osteoblast-like MG-63 cell culture. The HAp-coated HNS stimulated the alkaline-phosphate activity of the MG-63 culture after 7 days. Therefore, HAp-coated HNS is suitable for orthopedic devices and soft tissue adhesion materials.",

keywords = "chemical solution deposition, hydroxyapatite, nickel-free high-nitrogen stainless steel, surface modification",

author = "Makoto Sasaki and Motoki Inoue and Yasuyuki Katada and Yuuki Nishida and Akiyoshi Taniguchi and Sachiko Hiromoto and Tetsushi Taguchi",

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doi = "10.1088/1468-6996/13/6/064213",

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T1 - Preparation and biological evaluation of hydroxyapatite-coated nickel-free high-nitrogen stainless steel

AU - Sasaki, Makoto

AU - Inoue, Motoki

AU - Katada, Yasuyuki

AU - Nishida, Yuuki

AU - Taniguchi, Akiyoshi

AU - Hiromoto, Sachiko

AU - Taguchi, Tetsushi

PY - 2012/12

Y1 - 2012/12

N2 - Calcium phosphate was formed on nickel-free high-nitrogen stainless steel (HNS) by chemical solution deposition. The calcium phosphate deposition was enhanced by glutamic acid covalently immobilized on the surface of HNS with trisuccinimidyl citrate as a linker. X-ray diffraction patterns and Fourier transform infrared spectra showed that the material deposited on glutamic acid-immobilized HNS within 24 h was low-crystallinity calcium-deficient carbonate-containing hydroxyapatite (HAp). The biological activity of the resulting HAp-coated HNS was investigated by using a human osteoblast-like MG-63 cell culture. The HAp-coated HNS stimulated the alkaline-phosphate activity of the MG-63 culture after 7 days. Therefore, HAp-coated HNS is suitable for orthopedic devices and soft tissue adhesion materials.

AB - Calcium phosphate was formed on nickel-free high-nitrogen stainless steel (HNS) by chemical solution deposition. The calcium phosphate deposition was enhanced by glutamic acid covalently immobilized on the surface of HNS with trisuccinimidyl citrate as a linker. X-ray diffraction patterns and Fourier transform infrared spectra showed that the material deposited on glutamic acid-immobilized HNS within 24 h was low-crystallinity calcium-deficient carbonate-containing hydroxyapatite (HAp). The biological activity of the resulting HAp-coated HNS was investigated by using a human osteoblast-like MG-63 cell culture. The HAp-coated HNS stimulated the alkaline-phosphate activity of the MG-63 culture after 7 days. Therefore, HAp-coated HNS is suitable for orthopedic devices and soft tissue adhesion materials.

KW - chemical solution deposition

KW - hydroxyapatite

KW - nickel-free high-nitrogen stainless steel

KW - surface modification

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SN - 1468-6996

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JO - Science and Technology of Advanced Materials

JF - Science and Technology of Advanced Materials

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M1 - 064213

ER -

Preparation and biological evaluation of hydroxyapatite-coated nickel-free high-nitrogen stainless steel

Abstract

Keywords

ASJC Scopus subject areas

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