Preparation of colloidal mesoporous silica nanoparticles with different diameters and their unique degradation behavior in static aqueous systems

Hironori Yamada, Chihiro Urata, Yuko Aoyama, Shimon Osada, Yusuke Yamauchi, Kazuyuki Kuroda

    Research output: Contribution to journalArticle

    161 Citations (Scopus)

    Abstract

    The degradation of colloidal mesoporous silica nanoparticles (CMPS) is quite important for the design of stable catalyst supports and biodegradable drug delivery systems carriers. The degradation of various silica nanoparticles in static aqueous systems was investigated. The condition was achieved through the use of a dialysis tube. Four types of CMPS with different particle diameters (ca. 20-80 nm) were newly prepared from tetraalkoxysilanes (Si(OR) 4, R = Me, Et, Pr, and Bu) at different hydrolysis rates by a one-pot synthesis. Larger particles were formed by using tetraalkoxysilanes at slower hydrolysis rates because particle growth dominates nucleation. The degradation of CMPS is independent of diameter differences. The degradation rate of CMPS is higher than that of colloidal nonporous silica nanoparticles with smaller diameters because of the presence of mesopores. CMPS are also more degradable than aggregated CMPS because of colloidal dispersity. Moreover, it was confirmed for the first time that the degradation simultaneously proceeds from the outer as well as the inner surfaces of CMPS and that the mesostructure and morphology are partly retained even after more than half of the CMPS are degraded. The information on the degradation reported here is quite useful for the design of silica-based nanomaterials with tunable degradability/stability.

    Original languageEnglish
    Pages (from-to)1462-1471
    Number of pages10
    JournalChemistry of Materials
    Volume24
    Issue number8
    DOIs
    Publication statusPublished - 2012 Apr 24

    Fingerprint

    Silicon Dioxide
    Silica
    Nanoparticles
    Degradation
    Hydrolysis
    Dialysis
    Catalyst supports
    Nanostructured materials
    Nucleation

    Keywords

    • aqueous systems
    • behavior
    • colloidal mesoporous silica nanoparticles
    • degradation

    ASJC Scopus subject areas

    • Materials Chemistry
    • Chemical Engineering(all)
    • Chemistry(all)

    Cite this

    Preparation of colloidal mesoporous silica nanoparticles with different diameters and their unique degradation behavior in static aqueous systems. / Yamada, Hironori; Urata, Chihiro; Aoyama, Yuko; Osada, Shimon; Yamauchi, Yusuke; Kuroda, Kazuyuki.

    In: Chemistry of Materials, Vol. 24, No. 8, 24.04.2012, p. 1462-1471.

    Research output: Contribution to journalArticle

    Yamada, Hironori ; Urata, Chihiro ; Aoyama, Yuko ; Osada, Shimon ; Yamauchi, Yusuke ; Kuroda, Kazuyuki. / Preparation of colloidal mesoporous silica nanoparticles with different diameters and their unique degradation behavior in static aqueous systems. In: Chemistry of Materials. 2012 ; Vol. 24, No. 8. pp. 1462-1471.
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