Preparation of methotrexate-encapsulated liposomes and evaluation of their properties

Kvoko Kaiyama; Izumi Sato; Shinji Takeoka

Preparation of methotrexate-encapsulated liposomes and evaluation of their properties

Kvoko Kaiyama^*, Izumi Sato, Shinji Takeoka

^*Corresponding author for this work

School of Advanced Science and Engineering

Research output: Contribution to conference › Paper › peer-review

Abstract

We are preparing immunoliposomes which encapsulate anticancer methotrexate to provide an efficient intracellular drug delivery system (DDS) in tumor cells. In this paper, concentrated methotrexate was encapsulated into liposomes by an extrusion method. We also evaluated properties of the liposomes such as particle size, encapsulation efficiency, dispersibility, and the leakage of MIX from liposomes.

Original language	English
Number of pages	1
Publication status	Published - 2006 Dec 1
Event	55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan Duration: 2006 Sept 20 → 2006 Sept 22

Other

Other	55th Society of Polymer Science Japan Symposium on Macromolecules
Country/Territory	Japan
City	Toyama
Period	06/9/20 → 06/9/22

Keywords

Anticancer
DDS
Liposomes
Methotrexate
Vesicles

ASJC Scopus subject areas

Engineering(all)

Cite this

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title = "Preparation of methotrexate-encapsulated liposomes and evaluation of their properties",

abstract = "We are preparing immunoliposomes which encapsulate anticancer methotrexate to provide an efficient intracellular drug delivery system (DDS) in tumor cells. In this paper, concentrated methotrexate was encapsulated into liposomes by an extrusion method. We also evaluated properties of the liposomes such as particle size, encapsulation efficiency, dispersibility, and the leakage of MIX from liposomes.",

keywords = "Anticancer, DDS, Liposomes, Methotrexate, Vesicles",

author = "Kvoko Kaiyama and Izumi Sato and Shinji Takeoka",

year = "2006",

month = dec,

day = "1",

language = "English",

note = "55th Society of Polymer Science Japan Symposium on Macromolecules ; Conference date: 20-09-2006 Through 22-09-2006",

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TY - CONF

T1 - Preparation of methotrexate-encapsulated liposomes and evaluation of their properties

AU - Kaiyama, Kvoko

AU - Sato, Izumi

AU - Takeoka, Shinji

PY - 2006/12/1

Y1 - 2006/12/1

N2 - We are preparing immunoliposomes which encapsulate anticancer methotrexate to provide an efficient intracellular drug delivery system (DDS) in tumor cells. In this paper, concentrated methotrexate was encapsulated into liposomes by an extrusion method. We also evaluated properties of the liposomes such as particle size, encapsulation efficiency, dispersibility, and the leakage of MIX from liposomes.

AB - We are preparing immunoliposomes which encapsulate anticancer methotrexate to provide an efficient intracellular drug delivery system (DDS) in tumor cells. In this paper, concentrated methotrexate was encapsulated into liposomes by an extrusion method. We also evaluated properties of the liposomes such as particle size, encapsulation efficiency, dispersibility, and the leakage of MIX from liposomes.

KW - Anticancer

KW - DDS

KW - Liposomes

KW - Methotrexate

KW - Vesicles

UR - http://www.scopus.com/inward/record.url?scp=33846169451&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846169451&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:33846169451

T2 - 55th Society of Polymer Science Japan Symposium on Macromolecules

Y2 - 20 September 2006 through 22 September 2006

ER -

Preparation of methotrexate-encapsulated liposomes and evaluation of their properties

Abstract

Other

Keywords

ASJC Scopus subject areas

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