Preventing complications from high-dose rate brachytherapy when treating mobile tongue cancer via the application of a modular lead-lined spacer

Shumei Murakami, Rinus G. Verdonschot, Naoya Kakimoto, Iori Sumida, Masateru Fujiwara, Kazuhiko Ogawa, Souhei Furukawa

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

Purpose: To point out the advantages and drawbacks of high-dose rate brachytherapy in the treatment of mobile tongue cancer and indicate the clinical importance of modular lead-lined spacers when applying this technique to patients. Methods: First, all basic steps to construct the modular spacer are shown. Second, we simulate and evaluate the dose rate reduction for a wide range of spacer configurations. Results: With increasing distance to the source absorbed doses dropped considerably. Significantly more shielding was obtained when lead was added to the spacer and this effect was most pronounced on shorter (i.e. more clinically relevant) distances to the source. Conclusions: The modular spacer represents an important addition to the planning and treatment stages of mobile tongue cancer using HDR-ISBT.

Original languageEnglish
Article numbere0154226
JournalPLoS One
Volume11
Issue number4
DOIs
Publication statusPublished - 2016 Apr 1
Externally publishedYes

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

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