Abstract
Vascular structures are essential for the survival of thick artificial three-dimensional (3D) tissues. However, it is difficult to create high-cell-density artificial tissue with vascular structures of a few hundred micrometers in diameter. Bioprinting technology can create artificial 3D tissues with vascular structures of a few hundred micrometers in diameter, but the cell density of bio-printed artificial 3D tissues is low. On the other hand, cell sheet technology can create high-cell-density artificial 3D tissues by stacking, but it is not possible to set small vascular structures at any place. In this study, we successfully demonstrated high-cell-density artificial 3D tissues with vascular-like structures by stacking cell sheets combined with bioprinting technology.
Original language | English |
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Pages (from-to) | 199-203 |
Number of pages | 5 |
Journal | Artificial Life and Robotics |
Volume | 25 |
Issue number | 2 |
DOIs | |
Publication status | Published - 2020 May 1 |
Keywords
- Bioprinting
- Cell sheet
- Support hydrogel
- Vascular-like structure
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Artificial Intelligence