Programmable Medicine

Autonomous, Ingestible, Deployable Hydrogel Patch and Plug for Stomach Ulcer Therapy

Alexis Du Plessis D'Argentre, Samuel Perry, Yoshitaka Iwata, Haruna Iwasaki, Eiji Iwase, Assunta Fabozzo, Iain Will, Daniela Rus, Dana D. Damian, Shuhei Miyashita

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    1 Citation (Scopus)

    Abstract

    Gastric ulcer is a chronic and complex (and often complete) erosion of the stomach wall that happens as a complication of a previous chronic, inflammatory process. It represents a catastrophic situation in which the patient is critical and its conditions need to be treated fast. This study presents a remotely navigatable and deployable ingestible patch and plug for gastric ulcer treatment. The patch/plug structure is made of agarose hydrogel that can change rigidity through hydration and dehydration. When dehydrated, it is rigid and can maintain a folded configuration so it can be ingested as a 'pill'. This can be guided to the targeted location by a magnetic field, and be deployed instantly by hydration, namely by supplying water from the mouth. Due to the deployable origami design, it exhibits an expansion of 10 times its initial surface area, making the device suitable for the use of dressing a surface as a patch, and filling a hole as a plug.

    Original languageEnglish
    Title of host publication2018 IEEE International Conference on Robotics and Automation, ICRA 2018
    PublisherInstitute of Electrical and Electronics Engineers Inc.
    Pages1511-1518
    Number of pages8
    ISBN (Electronic)9781538630815
    DOIs
    Publication statusPublished - 2018 Sep 10
    Event2018 IEEE International Conference on Robotics and Automation, ICRA 2018 - Brisbane, Australia
    Duration: 2018 May 212018 May 25

    Publication series

    NameProceedings - IEEE International Conference on Robotics and Automation
    ISSN (Print)1050-4729

    Conference

    Conference2018 IEEE International Conference on Robotics and Automation, ICRA 2018
    CountryAustralia
    CityBrisbane
    Period18/5/2118/5/25

    Fingerprint

    Hydrogels
    Hydration
    Medicine
    Dehydration
    Rigidity
    Erosion
    Magnetic fields
    Water

    ASJC Scopus subject areas

    • Software
    • Control and Systems Engineering
    • Artificial Intelligence
    • Electrical and Electronic Engineering

    Cite this

    D'Argentre, A. D. P., Perry, S., Iwata, Y., Iwasaki, H., Iwase, E., Fabozzo, A., ... Miyashita, S. (2018). Programmable Medicine: Autonomous, Ingestible, Deployable Hydrogel Patch and Plug for Stomach Ulcer Therapy. In 2018 IEEE International Conference on Robotics and Automation, ICRA 2018 (pp. 1511-1518). [8460615] (Proceedings - IEEE International Conference on Robotics and Automation). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ICRA.2018.8460615

    Programmable Medicine : Autonomous, Ingestible, Deployable Hydrogel Patch and Plug for Stomach Ulcer Therapy. / D'Argentre, Alexis Du Plessis; Perry, Samuel; Iwata, Yoshitaka; Iwasaki, Haruna; Iwase, Eiji; Fabozzo, Assunta; Will, Iain; Rus, Daniela; Damian, Dana D.; Miyashita, Shuhei.

    2018 IEEE International Conference on Robotics and Automation, ICRA 2018. Institute of Electrical and Electronics Engineers Inc., 2018. p. 1511-1518 8460615 (Proceedings - IEEE International Conference on Robotics and Automation).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    D'Argentre, ADP, Perry, S, Iwata, Y, Iwasaki, H, Iwase, E, Fabozzo, A, Will, I, Rus, D, Damian, DD & Miyashita, S 2018, Programmable Medicine: Autonomous, Ingestible, Deployable Hydrogel Patch and Plug for Stomach Ulcer Therapy. in 2018 IEEE International Conference on Robotics and Automation, ICRA 2018., 8460615, Proceedings - IEEE International Conference on Robotics and Automation, Institute of Electrical and Electronics Engineers Inc., pp. 1511-1518, 2018 IEEE International Conference on Robotics and Automation, ICRA 2018, Brisbane, Australia, 18/5/21. https://doi.org/10.1109/ICRA.2018.8460615
    D'Argentre ADP, Perry S, Iwata Y, Iwasaki H, Iwase E, Fabozzo A et al. Programmable Medicine: Autonomous, Ingestible, Deployable Hydrogel Patch and Plug for Stomach Ulcer Therapy. In 2018 IEEE International Conference on Robotics and Automation, ICRA 2018. Institute of Electrical and Electronics Engineers Inc. 2018. p. 1511-1518. 8460615. (Proceedings - IEEE International Conference on Robotics and Automation). https://doi.org/10.1109/ICRA.2018.8460615
    D'Argentre, Alexis Du Plessis ; Perry, Samuel ; Iwata, Yoshitaka ; Iwasaki, Haruna ; Iwase, Eiji ; Fabozzo, Assunta ; Will, Iain ; Rus, Daniela ; Damian, Dana D. ; Miyashita, Shuhei. / Programmable Medicine : Autonomous, Ingestible, Deployable Hydrogel Patch and Plug for Stomach Ulcer Therapy. 2018 IEEE International Conference on Robotics and Automation, ICRA 2018. Institute of Electrical and Electronics Engineers Inc., 2018. pp. 1511-1518 (Proceedings - IEEE International Conference on Robotics and Automation).
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    AU - Iwase, Eiji

    AU - Fabozzo, Assunta

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