Properties of secondary vestibular neurons fired by stimulation of ampullary nerve of the vertical, anterior or posterior, semicircular canals in the cat

Yoshio Uchino, Naoki Hirai, Shuji Suzuki, Shiroh Watanabe

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Experiments on cats were performed to study the pathway and location of the secondary vestibulo-ocular neurons in response to stimulation of the ampullary nerves of the vertical, anterior or posterior, semicircular canals. Experiments on the medial longitudinal fasciculus transection disclosed that vertical canal-evoked, disynaptic excitation and inhibition were transmitted to the extraocular motoneurons through the contra- and ipsilateral medial longitudinal fasciculus respectively. Secondary vestibular neurons, which receive input from the ampullary nerve of the vertical semicircular canals and send their axons to contralateral medial longitudinal fasciculus, were intermingled in the rostral half of the descending and lateral part of the medial vestibular nuclei. A direct excitatory connection of some of these neurons to the target extraocular motoneurons was confirmed by means of a spike-triggered signal averaging technique. It was also found that neurons activated by antidromic stimulation of ipsilateral medial longitudinal fasciculus were located in the superior vestibular nucleus, some of which made direct inhibitory connections to the target extraocular motoneurons. Both excitatory and inhibitory vestibuloocular neurons made synaptic contact in about half of the impaled target motoneurons.

Original languageEnglish
Pages (from-to)273-286
Number of pages14
JournalBrain Research
Volume223
Issue number2
DOIs
Publication statusPublished - 1981 Nov 2
Externally publishedYes

Fingerprint

Semicircular Canals
Motor Neurons
Cats
Neurons
Vestibular Nuclei
Axons

Keywords

  • descending, medial, superior nuclei
  • extraocular motoneurons
  • MLF
  • unitary PSPs
  • vertical canal
  • vestibular neurons

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Properties of secondary vestibular neurons fired by stimulation of ampullary nerve of the vertical, anterior or posterior, semicircular canals in the cat. / Uchino, Yoshio; Hirai, Naoki; Suzuki, Shuji; Watanabe, Shiroh.

In: Brain Research, Vol. 223, No. 2, 02.11.1981, p. 273-286.

Research output: Contribution to journalArticle

Uchino, Yoshio ; Hirai, Naoki ; Suzuki, Shuji ; Watanabe, Shiroh. / Properties of secondary vestibular neurons fired by stimulation of ampullary nerve of the vertical, anterior or posterior, semicircular canals in the cat. In: Brain Research. 1981 ; Vol. 223, No. 2. pp. 273-286.
@article{9a5632e8857a4973b30264788e78182d,
title = "Properties of secondary vestibular neurons fired by stimulation of ampullary nerve of the vertical, anterior or posterior, semicircular canals in the cat",
abstract = "Experiments on cats were performed to study the pathway and location of the secondary vestibulo-ocular neurons in response to stimulation of the ampullary nerves of the vertical, anterior or posterior, semicircular canals. Experiments on the medial longitudinal fasciculus transection disclosed that vertical canal-evoked, disynaptic excitation and inhibition were transmitted to the extraocular motoneurons through the contra- and ipsilateral medial longitudinal fasciculus respectively. Secondary vestibular neurons, which receive input from the ampullary nerve of the vertical semicircular canals and send their axons to contralateral medial longitudinal fasciculus, were intermingled in the rostral half of the descending and lateral part of the medial vestibular nuclei. A direct excitatory connection of some of these neurons to the target extraocular motoneurons was confirmed by means of a spike-triggered signal averaging technique. It was also found that neurons activated by antidromic stimulation of ipsilateral medial longitudinal fasciculus were located in the superior vestibular nucleus, some of which made direct inhibitory connections to the target extraocular motoneurons. Both excitatory and inhibitory vestibuloocular neurons made synaptic contact in about half of the impaled target motoneurons.",
keywords = "descending, medial, superior nuclei, extraocular motoneurons, MLF, unitary PSPs, vertical canal, vestibular neurons",
author = "Yoshio Uchino and Naoki Hirai and Shuji Suzuki and Shiroh Watanabe",
year = "1981",
month = "11",
day = "2",
doi = "10.1016/0006-8993(81)91141-0",
language = "English",
volume = "223",
pages = "273--286",
journal = "Brain Research",
issn = "0006-8993",
publisher = "Elsevier",
number = "2",

}

TY - JOUR

T1 - Properties of secondary vestibular neurons fired by stimulation of ampullary nerve of the vertical, anterior or posterior, semicircular canals in the cat

AU - Uchino, Yoshio

AU - Hirai, Naoki

AU - Suzuki, Shuji

AU - Watanabe, Shiroh

PY - 1981/11/2

Y1 - 1981/11/2

N2 - Experiments on cats were performed to study the pathway and location of the secondary vestibulo-ocular neurons in response to stimulation of the ampullary nerves of the vertical, anterior or posterior, semicircular canals. Experiments on the medial longitudinal fasciculus transection disclosed that vertical canal-evoked, disynaptic excitation and inhibition were transmitted to the extraocular motoneurons through the contra- and ipsilateral medial longitudinal fasciculus respectively. Secondary vestibular neurons, which receive input from the ampullary nerve of the vertical semicircular canals and send their axons to contralateral medial longitudinal fasciculus, were intermingled in the rostral half of the descending and lateral part of the medial vestibular nuclei. A direct excitatory connection of some of these neurons to the target extraocular motoneurons was confirmed by means of a spike-triggered signal averaging technique. It was also found that neurons activated by antidromic stimulation of ipsilateral medial longitudinal fasciculus were located in the superior vestibular nucleus, some of which made direct inhibitory connections to the target extraocular motoneurons. Both excitatory and inhibitory vestibuloocular neurons made synaptic contact in about half of the impaled target motoneurons.

AB - Experiments on cats were performed to study the pathway and location of the secondary vestibulo-ocular neurons in response to stimulation of the ampullary nerves of the vertical, anterior or posterior, semicircular canals. Experiments on the medial longitudinal fasciculus transection disclosed that vertical canal-evoked, disynaptic excitation and inhibition were transmitted to the extraocular motoneurons through the contra- and ipsilateral medial longitudinal fasciculus respectively. Secondary vestibular neurons, which receive input from the ampullary nerve of the vertical semicircular canals and send their axons to contralateral medial longitudinal fasciculus, were intermingled in the rostral half of the descending and lateral part of the medial vestibular nuclei. A direct excitatory connection of some of these neurons to the target extraocular motoneurons was confirmed by means of a spike-triggered signal averaging technique. It was also found that neurons activated by antidromic stimulation of ipsilateral medial longitudinal fasciculus were located in the superior vestibular nucleus, some of which made direct inhibitory connections to the target extraocular motoneurons. Both excitatory and inhibitory vestibuloocular neurons made synaptic contact in about half of the impaled target motoneurons.

KW - descending, medial, superior nuclei

KW - extraocular motoneurons

KW - MLF

KW - unitary PSPs

KW - vertical canal

KW - vestibular neurons

UR - http://www.scopus.com/inward/record.url?scp=0019490075&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019490075&partnerID=8YFLogxK

U2 - 10.1016/0006-8993(81)91141-0

DO - 10.1016/0006-8993(81)91141-0

M3 - Article

C2 - 7284812

AN - SCOPUS:0019490075

VL - 223

SP - 273

EP - 286

JO - Brain Research

JF - Brain Research

SN - 0006-8993

IS - 2

ER -