Rate parameters for oxygen and carbon monoxide binding to a liposome-embedded heme under physiological conditions

Eishun Tsuchida, Makoto Yuasa, Hiroyuki Nishide

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Abstract

Rate parameters for oxygen and carbon monoxide binding to a liposome-embedded heme were measured under physiological conditions (pH 7.0 at 37 °C) by stopped-flow spectrophotometry. The rate constants were similar to those of red blood cells in suspension. It is concluded that liposome-embedded heme is a suitable model to study the binding of gaseous molecules to red blood cells.

Original languageEnglish
Pages (from-to)65-68
Number of pages4
JournalJournal of the Chemical Society, Dalton Transactions
Issue number1
DOIs
Publication statusPublished - 1985

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Carbon Monoxide
Heme
Liposomes
Blood
Cells
Oxygen
Spectrophotometry
Rate constants
Suspensions
Molecules

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

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abstract = "Rate parameters for oxygen and carbon monoxide binding to a liposome-embedded heme were measured under physiological conditions (pH 7.0 at 37 °C) by stopped-flow spectrophotometry. The rate constants were similar to those of red blood cells in suspension. It is concluded that liposome-embedded heme is a suitable model to study the binding of gaseous molecules to red blood cells.",
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