TY - GEN
T1 - Real-time measurements of VOC exposure and heart rate variability in indoor and outdoor environments
AU - Mizukoshi, Atsushi
AU - Kumagai, Kazukiyo
AU - Yamamoto, Naomichi
AU - Noguchi, Miyuki
AU - Yoshiuchi, Kazuhiro
AU - Kumano, Hiroaki
AU - Yanagisawa, Yukio
PY - 2007/12/1
Y1 - 2007/12/1
N2 - While various VOCs are known to show neurotoxic effects, the detailed mechanisms of VOCs on autonomic nervous system have not been fully understood partly because objective and quantitative measures to indicate neural abnormalities are still under development. Nevertheless, heart rate variability (HRV) has been recently proposed as an indicative measure of the autonomic defect. In this study, we used HRV as an indicative measure of the autonomic defect to relate their values to the personal concentrations of VOCs measured by a real-time VOC monitor. The measurements were conducted to 7 healthy subjects for 24 hours. The results showed HF powers were decreased for 6 subjects when the TVOC concentration changes were high, indicating the suppression of parasympathetic nervous induced by the exposure to VOCs. The present study indicated these real-time monitoring was useful to characterize the trends of VOC exposures and their effects on autonomic nervous system. Application of the present method is expected to lead to diagnosis and cure for the patients such as MCS and sick building syndrome in the future.
AB - While various VOCs are known to show neurotoxic effects, the detailed mechanisms of VOCs on autonomic nervous system have not been fully understood partly because objective and quantitative measures to indicate neural abnormalities are still under development. Nevertheless, heart rate variability (HRV) has been recently proposed as an indicative measure of the autonomic defect. In this study, we used HRV as an indicative measure of the autonomic defect to relate their values to the personal concentrations of VOCs measured by a real-time VOC monitor. The measurements were conducted to 7 healthy subjects for 24 hours. The results showed HF powers were decreased for 6 subjects when the TVOC concentration changes were high, indicating the suppression of parasympathetic nervous induced by the exposure to VOCs. The present study indicated these real-time monitoring was useful to characterize the trends of VOC exposures and their effects on autonomic nervous system. Application of the present method is expected to lead to diagnosis and cure for the patients such as MCS and sick building syndrome in the future.
KW - Heart rate variability (HRV)
KW - Hotter monitor
KW - Real-time assessment
KW - VOCs
UR - http://www.scopus.com/inward/record.url?scp=84857310157&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84857310157&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84857310157
SN - 9784861630705
T3 - IAQVEC 2007 Proceedings - 6th International Conference on Indoor Air Quality, Ventilation and Energy Conservation in Buildings: Sustainable Built Environment
SP - 519
EP - 522
BT - IAQVEC 2007 Proceedings - 6th International Conference on Indoor Air Quality, Ventilation and Energy Conservation in Buildings
T2 - 6th International Conference on Indoor Air Quality, Ventilation and Energy Conservation in Buildings: Sustainable Built Environment, IAQVEC 2007
Y2 - 28 October 2007 through 31 October 2007
ER -
