## Abstract

A system has been developed to rapidly calculate functional images of parametric rate constants, without dynamic scan in 3D PET, and implementation of this system was tested in a clinical study following O-15 water administration. The technique is based on the weighted-integration algorithms derived for the 2- and 3-compartment models. The system consists of large-scale memory (1 GBytes) and a micro-processor that is capable of acquiring, transferring and making arbitrary arithmetic calculations during data acquisition, providing multiple time-weighted 3D-sinograms in real-time. These sinograms are reconstructed, and inserted into operational equations, thus generating parametric rate-constant images. This technique was found to reliably provide quantitative parametric rate-constant images in 3D PET, and thus would be useful for routine clinical use of 3D PET.

Original language | English |
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Pages | 1675-1679 |

Number of pages | 5 |

Publication status | Published - 1995 |

Externally published | Yes |

Event | Proceedings of the 1995 IEEE Nuclear Science Symposium and Medical Imaging Conference. Part 1 (of 3) - San Francisco, CA, USA Duration: 1995 Oct 21 → 1995 Oct 28 |

### Conference

Conference | Proceedings of the 1995 IEEE Nuclear Science Symposium and Medical Imaging Conference. Part 1 (of 3) |
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City | San Francisco, CA, USA |

Period | 95/10/21 → 95/10/28 |

## ASJC Scopus subject areas

- Radiation
- Nuclear and High Energy Physics
- Radiology Nuclear Medicine and imaging