Abstract
Enantioselective cycloaddition using chiral transition metal catalysts is an atom-economical and efficient synthetic tool for the construction of chiral carbo- and heterocyclic skeletons. This short account discloses our recent results of inter- and intramolecular enantioselective [2 + 2 + 2] cycloadditions of alkyne and/or alkene moiety(ies). Chiral iridium complexes catalyzed the alkyne trimerization for the generation of axial chirality(ies), and chiral rhodium ones catalyzed alkyne-alkyne-alkene cyclization for the generation of a quaternary carbon including spirocyclic system.
| Original language | English |
|---|---|
| Pages (from-to) | 1317-1323 |
| Number of pages | 7 |
| Journal | Organic and Biomolecular Chemistry |
| Volume | 6 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - 2008 |
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ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Chemistry(all)
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Recent advances in enantioselective [2 + 2 + 2] cycloaddition. / Shibata, Takanori; Tsuchikama, Kyoji.
In: Organic and Biomolecular Chemistry, Vol. 6, No. 8, 2008, p. 1317-1323.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Recent advances in enantioselective [2 + 2 + 2] cycloaddition
AU - Shibata, Takanori
AU - Tsuchikama, Kyoji
PY - 2008
Y1 - 2008
N2 - Enantioselective cycloaddition using chiral transition metal catalysts is an atom-economical and efficient synthetic tool for the construction of chiral carbo- and heterocyclic skeletons. This short account discloses our recent results of inter- and intramolecular enantioselective [2 + 2 + 2] cycloadditions of alkyne and/or alkene moiety(ies). Chiral iridium complexes catalyzed the alkyne trimerization for the generation of axial chirality(ies), and chiral rhodium ones catalyzed alkyne-alkyne-alkene cyclization for the generation of a quaternary carbon including spirocyclic system.
AB - Enantioselective cycloaddition using chiral transition metal catalysts is an atom-economical and efficient synthetic tool for the construction of chiral carbo- and heterocyclic skeletons. This short account discloses our recent results of inter- and intramolecular enantioselective [2 + 2 + 2] cycloadditions of alkyne and/or alkene moiety(ies). Chiral iridium complexes catalyzed the alkyne trimerization for the generation of axial chirality(ies), and chiral rhodium ones catalyzed alkyne-alkyne-alkene cyclization for the generation of a quaternary carbon including spirocyclic system.
UR - http://www.scopus.com/inward/record.url?scp=41549116352&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=41549116352&partnerID=8YFLogxK
U2 - 10.1039/b720031e
DO - 10.1039/b720031e
M3 - Article
C2 - 18385836
AN - SCOPUS:41549116352
VL - 6
SP - 1317
EP - 1323
JO - Organic and Biomolecular Chemistry
JF - Organic and Biomolecular Chemistry
SN - 1477-0520
IS - 8
ER -