Abstract
Enantioselective cycloaddition using chiral transition metal catalysts is an atom-economical and efficient synthetic tool for the construction of chiral carbo- and heterocyclic skeletons. This short account discloses our recent results of inter- and intramolecular enantioselective [2 + 2 + 2] cycloadditions of alkyne and/or alkene moiety(ies). Chiral iridium complexes catalyzed the alkyne trimerization for the generation of axial chirality(ies), and chiral rhodium ones catalyzed alkyne-alkyne-alkene cyclization for the generation of a quaternary carbon including spirocyclic system.
| Original language | English |
|---|---|
| Pages (from-to) | 1317-1323 |
| Number of pages | 7 |
| Journal | Organic and Biomolecular Chemistry |
| Volume | 6 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - 2008 Apr 8 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
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Shibata, T., & Tsuchikama, K. (2008). Recent advances in enantioselective [2 + 2 + 2] cycloaddition. Organic and Biomolecular Chemistry, 6(8), 1317-1323. https://doi.org/10.1039/b720031e