Abstract
Most temperate-zone species use photoperiod to coordinate breeding and ensure that offspring are born during favourable conditions. Although photoperiodic influences on the reproductive axis have been well characterized, the precise mechanisms by which photoperiodic information and other seasonal cues are integrated to regulate reproductive function remain less well specified. Two recently discovered neuropeptides, kisspeptin and gonadotropin-inhibitory hormone, have pronounced opposing influences on reproductive function. This paper will review recent evidence for a role of these peptides in seasonal reproduction and propose a theoretical framework by which these novel regulatory peptides may serve to regulate seasonal breeding. Understanding the mechanisms regulating appropriate changes in reproductive status will serve to advance a wide range of life science disciplines.
Original language | English |
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Pages (from-to) | 1943-1951 |
Number of pages | 9 |
Journal | Proceedings of the Royal Society B: Biological Sciences |
Volume | 275 |
Issue number | 1646 |
DOIs | |
Publication status | Published - 2008 Sep 7 |
Keywords
- Gonadotropin-inhibitory hormone
- Kisspeptin
- Metastin
- RFamide
- RFamide-related peptide
- Seasonal reproduction
ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)
- Agricultural and Biological Sciences (miscellaneous)