Recent advances in reproductive neuroendocrinology

A role for RFamide peptides in seasonal reproduction?

Timothy J. Greives, Lance J. Kriegsfeld, George E. Bentley, Kazuyoshi Tsutsui, Gregory E. Demas

    Research output: Contribution to journalArticle

    31 Citations (Scopus)

    Abstract

    Most temperate-zone species use photoperiod to coordinate breeding and ensure that offspring are born during favourable conditions. Although photoperiodic influences on the reproductive axis have been well characterized, the precise mechanisms by which photoperiodic information and other seasonal cues are integrated to regulate reproductive function remain less well specified. Two recently discovered neuropeptides, kisspeptin and gonadotropin-inhibitory hormone, have pronounced opposing influences on reproductive function. This paper will review recent evidence for a role of these peptides in seasonal reproduction and propose a theoretical framework by which these novel regulatory peptides may serve to regulate seasonal breeding. Understanding the mechanisms regulating appropriate changes in reproductive status will serve to advance a wide range of life science disciplines.

    Original languageEnglish
    Pages (from-to)1943-1951
    Number of pages9
    JournalProceedings of the Royal Society B: Biological Sciences
    Volume275
    Issue number1646
    DOIs
    Publication statusPublished - 2008 Sep 7

    Fingerprint

    Neuroendocrinology
    peptide
    Breeding
    Reproduction
    Kisspeptins
    breeding
    peptides
    reproductive status
    life science
    Peptides
    Biological Science Disciplines
    Photoperiod
    neuropeptides
    gonadotropins
    photoperiod
    Neuropeptides
    temperate zones
    Gonadotropins
    hormone
    Cues

    Keywords

    • Gonadotropin-inhibitory hormone
    • Kisspeptin
    • Metastin
    • RFamide
    • RFamide-related peptide
    • Seasonal reproduction

    ASJC Scopus subject areas

    • Agricultural and Biological Sciences(all)
    • Agricultural and Biological Sciences (miscellaneous)

    Cite this

    Recent advances in reproductive neuroendocrinology : A role for RFamide peptides in seasonal reproduction? / Greives, Timothy J.; Kriegsfeld, Lance J.; Bentley, George E.; Tsutsui, Kazuyoshi; Demas, Gregory E.

    In: Proceedings of the Royal Society B: Biological Sciences, Vol. 275, No. 1646, 07.09.2008, p. 1943-1951.

    Research output: Contribution to journalArticle

    Greives, Timothy J. ; Kriegsfeld, Lance J. ; Bentley, George E. ; Tsutsui, Kazuyoshi ; Demas, Gregory E. / Recent advances in reproductive neuroendocrinology : A role for RFamide peptides in seasonal reproduction?. In: Proceedings of the Royal Society B: Biological Sciences. 2008 ; Vol. 275, No. 1646. pp. 1943-1951.
    @article{a5f185cabdb94f3490e2e8d153b3fc2e,
    title = "Recent advances in reproductive neuroendocrinology: A role for RFamide peptides in seasonal reproduction?",
    abstract = "Most temperate-zone species use photoperiod to coordinate breeding and ensure that offspring are born during favourable conditions. Although photoperiodic influences on the reproductive axis have been well characterized, the precise mechanisms by which photoperiodic information and other seasonal cues are integrated to regulate reproductive function remain less well specified. Two recently discovered neuropeptides, kisspeptin and gonadotropin-inhibitory hormone, have pronounced opposing influences on reproductive function. This paper will review recent evidence for a role of these peptides in seasonal reproduction and propose a theoretical framework by which these novel regulatory peptides may serve to regulate seasonal breeding. Understanding the mechanisms regulating appropriate changes in reproductive status will serve to advance a wide range of life science disciplines.",
    keywords = "Gonadotropin-inhibitory hormone, Kisspeptin, Metastin, RFamide, RFamide-related peptide, Seasonal reproduction",
    author = "Greives, {Timothy J.} and Kriegsfeld, {Lance J.} and Bentley, {George E.} and Kazuyoshi Tsutsui and Demas, {Gregory E.}",
    year = "2008",
    month = "9",
    day = "7",
    doi = "10.1098/rspb.2008.0433",
    language = "English",
    volume = "275",
    pages = "1943--1951",
    journal = "Philosophical Transactions of the Royal Society B: Biological Sciences",
    issn = "0962-8436",
    publisher = "Royal Society of London",
    number = "1646",

    }

    TY - JOUR

    T1 - Recent advances in reproductive neuroendocrinology

    T2 - A role for RFamide peptides in seasonal reproduction?

    AU - Greives, Timothy J.

    AU - Kriegsfeld, Lance J.

    AU - Bentley, George E.

    AU - Tsutsui, Kazuyoshi

    AU - Demas, Gregory E.

    PY - 2008/9/7

    Y1 - 2008/9/7

    N2 - Most temperate-zone species use photoperiod to coordinate breeding and ensure that offspring are born during favourable conditions. Although photoperiodic influences on the reproductive axis have been well characterized, the precise mechanisms by which photoperiodic information and other seasonal cues are integrated to regulate reproductive function remain less well specified. Two recently discovered neuropeptides, kisspeptin and gonadotropin-inhibitory hormone, have pronounced opposing influences on reproductive function. This paper will review recent evidence for a role of these peptides in seasonal reproduction and propose a theoretical framework by which these novel regulatory peptides may serve to regulate seasonal breeding. Understanding the mechanisms regulating appropriate changes in reproductive status will serve to advance a wide range of life science disciplines.

    AB - Most temperate-zone species use photoperiod to coordinate breeding and ensure that offspring are born during favourable conditions. Although photoperiodic influences on the reproductive axis have been well characterized, the precise mechanisms by which photoperiodic information and other seasonal cues are integrated to regulate reproductive function remain less well specified. Two recently discovered neuropeptides, kisspeptin and gonadotropin-inhibitory hormone, have pronounced opposing influences on reproductive function. This paper will review recent evidence for a role of these peptides in seasonal reproduction and propose a theoretical framework by which these novel regulatory peptides may serve to regulate seasonal breeding. Understanding the mechanisms regulating appropriate changes in reproductive status will serve to advance a wide range of life science disciplines.

    KW - Gonadotropin-inhibitory hormone

    KW - Kisspeptin

    KW - Metastin

    KW - RFamide

    KW - RFamide-related peptide

    KW - Seasonal reproduction

    UR - http://www.scopus.com/inward/record.url?scp=47249165971&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=47249165971&partnerID=8YFLogxK

    U2 - 10.1098/rspb.2008.0433

    DO - 10.1098/rspb.2008.0433

    M3 - Article

    VL - 275

    SP - 1943

    EP - 1951

    JO - Philosophical Transactions of the Royal Society B: Biological Sciences

    JF - Philosophical Transactions of the Royal Society B: Biological Sciences

    SN - 0962-8436

    IS - 1646

    ER -