Abstract
Most temperate-zone species use photoperiod to coordinate breeding and ensure that offspring are born during favourable conditions. Although photoperiodic influences on the reproductive axis have been well characterized, the precise mechanisms by which photoperiodic information and other seasonal cues are integrated to regulate reproductive function remain less well specified. Two recently discovered neuropeptides, kisspeptin and gonadotropin-inhibitory hormone, have pronounced opposing influences on reproductive function. This paper will review recent evidence for a role of these peptides in seasonal reproduction and propose a theoretical framework by which these novel regulatory peptides may serve to regulate seasonal breeding. Understanding the mechanisms regulating appropriate changes in reproductive status will serve to advance a wide range of life science disciplines.
| Original language | English |
|---|---|
| Pages (from-to) | 1943-1951 |
| Number of pages | 9 |
| Journal | Proceedings of the Royal Society B: Biological Sciences |
| Volume | 275 |
| Issue number | 1646 |
| DOIs | |
| Publication status | Published - 2008 Sep 7 |
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Keywords
- Gonadotropin-inhibitory hormone
- Kisspeptin
- Metastin
- RFamide
- RFamide-related peptide
- Seasonal reproduction
ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)
- Agricultural and Biological Sciences (miscellaneous)
Cite this
Recent advances in reproductive neuroendocrinology : A role for RFamide peptides in seasonal reproduction? / Greives, Timothy J.; Kriegsfeld, Lance J.; Bentley, George E.; Tsutsui, Kazuyoshi; Demas, Gregory E.
In: Proceedings of the Royal Society B: Biological Sciences, Vol. 275, No. 1646, 07.09.2008, p. 1943-1951.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Recent advances in reproductive neuroendocrinology
T2 - A role for RFamide peptides in seasonal reproduction?
AU - Greives, Timothy J.
AU - Kriegsfeld, Lance J.
AU - Bentley, George E.
AU - Tsutsui, Kazuyoshi
AU - Demas, Gregory E.
PY - 2008/9/7
Y1 - 2008/9/7
N2 - Most temperate-zone species use photoperiod to coordinate breeding and ensure that offspring are born during favourable conditions. Although photoperiodic influences on the reproductive axis have been well characterized, the precise mechanisms by which photoperiodic information and other seasonal cues are integrated to regulate reproductive function remain less well specified. Two recently discovered neuropeptides, kisspeptin and gonadotropin-inhibitory hormone, have pronounced opposing influences on reproductive function. This paper will review recent evidence for a role of these peptides in seasonal reproduction and propose a theoretical framework by which these novel regulatory peptides may serve to regulate seasonal breeding. Understanding the mechanisms regulating appropriate changes in reproductive status will serve to advance a wide range of life science disciplines.
AB - Most temperate-zone species use photoperiod to coordinate breeding and ensure that offspring are born during favourable conditions. Although photoperiodic influences on the reproductive axis have been well characterized, the precise mechanisms by which photoperiodic information and other seasonal cues are integrated to regulate reproductive function remain less well specified. Two recently discovered neuropeptides, kisspeptin and gonadotropin-inhibitory hormone, have pronounced opposing influences on reproductive function. This paper will review recent evidence for a role of these peptides in seasonal reproduction and propose a theoretical framework by which these novel regulatory peptides may serve to regulate seasonal breeding. Understanding the mechanisms regulating appropriate changes in reproductive status will serve to advance a wide range of life science disciplines.
KW - Gonadotropin-inhibitory hormone
KW - Kisspeptin
KW - Metastin
KW - RFamide
KW - RFamide-related peptide
KW - Seasonal reproduction
UR - http://www.scopus.com/inward/record.url?scp=47249165971&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=47249165971&partnerID=8YFLogxK
U2 - 10.1098/rspb.2008.0433
DO - 10.1098/rspb.2008.0433
M3 - Article
C2 - 18477543
AN - SCOPUS:47249165971
VL - 275
SP - 1943
EP - 1951
JO - Philosophical Transactions of the Royal Society B: Biological Sciences
JF - Philosophical Transactions of the Royal Society B: Biological Sciences
SN - 0962-8436
IS - 1646
ER -