Recurrence quantification analysis of dynamic brain networks

Marinho A. Lopes, Jiaxiang Zhang, Dominik Krzemiński, Khalid Hamandi, Qi Chen, Lorenzo Livi, Naoki Masuda

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Evidence suggests that brain network dynamics are a key determinant of brain function and dysfunction. Here we propose a new framework to assess the dynamics of brain networks based on recurrence analysis. Our framework uses recurrence plots and recurrence quantification analysis to characterize dynamic networks. For resting-state magnetoencephalographic dynamic functional networks (dFNs), we have found that functional networks recur more quickly in people with epilepsy than in healthy controls. This suggests that recurrence of dFNs may be used as a biomarker of epilepsy. For stereo electroencephalography data, we have found that dFNs involved in epileptic seizures emerge before seizure onset, and recurrence analysis allows us to detect seizures. We further observe distinct dFNs before and after seizures, which may inform neurostimulation strategies to prevent seizures. Our framework can also be used for understanding dFNs in healthy brain function and in other neurological disorders besides epilepsy.

Original languageEnglish
Pages (from-to)1040-1059
Number of pages20
JournalEuropean Journal of Neuroscience
Volume53
Issue number4
DOIs
Publication statusPublished - 2021 Feb
Externally publishedYes

Keywords

  • MEG
  • epilepsy
  • functional network
  • stereo EEG

ASJC Scopus subject areas

  • Neuroscience(all)

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