Reentrant conformational transitions in DNA molecules complexed with cationic surfactant

S. V. Mikhailenko, V. G. Sergeyev, K. Yoshikawa

Research output: Contribution to conferencePaper

Abstract

We have established the conditions for the dissociation-formation of DNA-CTAB complexes in organic solvents of different polarity. Fluorescence microscopy and CD spectroscopy indicate that DNA-CTAB complexes dissociate into their initial components at intermediate concentrations of alcohol, while conserving the double-stranded structure of native DNA. A further increase in the alcohol concentration leads to restoration of the complex, which is soluble under these conditions, i.e. in low-polarity organic media. As a novel phenomenon on DNA-CTAB interacting system, we have found the alcohol-induced reentrant globule-coil-globule transition in T4DNA-CTAB complexes.

Original languageEnglish
Pages213-215
Number of pages3
Publication statusPublished - 1998 Dec 1
Externally publishedYes
EventProceedings of the 1998 9th International Symposium on Micromechatronics and Human Science, MHS - Nagoya, Jpn
Duration: 1998 Nov 251998 Nov 28

Other

OtherProceedings of the 1998 9th International Symposium on Micromechatronics and Human Science, MHS
CityNagoya, Jpn
Period98/11/2598/11/28

ASJC Scopus subject areas

  • Engineering(all)

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    Mikhailenko, S. V., Sergeyev, V. G., & Yoshikawa, K. (1998). Reentrant conformational transitions in DNA molecules complexed with cationic surfactant. 213-215. Paper presented at Proceedings of the 1998 9th International Symposium on Micromechatronics and Human Science, MHS, Nagoya, Jpn, .