Reentrant conformational transitions in DNA molecules complexed with cationic surfactant

Sergey Mikhailenko, V. G. Sergeyev, K. Yoshikawa

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We have established the conditions for the dissociation-formation of DNA-CTAB complexes in organic solvents of different polarity. Fluorescence microscopy and CD spectroscopy indicate that DNA-CTAB complexes dissociate into their initial components at intermediate concentrations of alcohol, while conserving the double-stranded structure of native DNA. A further increase in the alcohol concentration leads to restoration of the complex, which is soluble under these conditions, i.e. in low-polarity organic media. As a novel phenomenon on DNA-CTAB interacting system, we have found the alcohol-induced reentrant globule-coil-globule transition in T4DNA-CTAB complexes.

Original languageEnglish
Title of host publicationProceedings of the International Symposium on Micromechatronics and Human Science
Place of PublicationPiscataway, NJ, United States
PublisherIEEE
Pages213-215
Number of pages3
Publication statusPublished - 1998
Externally publishedYes
EventProceedings of the 1998 9th International Symposium on Micromechatronics and Human Science, MHS - Nagoya, Jpn
Duration: 1998 Nov 251998 Nov 28

Other

OtherProceedings of the 1998 9th International Symposium on Micromechatronics and Human Science, MHS
CityNagoya, Jpn
Period98/11/2598/11/28

Fingerprint

Cationic surfactants
DNA
Molecules
Alcohols
Fluorescence microscopy
Organic solvents
Restoration
Spectroscopy

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Mikhailenko, S., Sergeyev, V. G., & Yoshikawa, K. (1998). Reentrant conformational transitions in DNA molecules complexed with cationic surfactant. In Proceedings of the International Symposium on Micromechatronics and Human Science (pp. 213-215). Piscataway, NJ, United States: IEEE.

Reentrant conformational transitions in DNA molecules complexed with cationic surfactant. / Mikhailenko, Sergey; Sergeyev, V. G.; Yoshikawa, K.

Proceedings of the International Symposium on Micromechatronics and Human Science. Piscataway, NJ, United States : IEEE, 1998. p. 213-215.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Mikhailenko, S, Sergeyev, VG & Yoshikawa, K 1998, Reentrant conformational transitions in DNA molecules complexed with cationic surfactant. in Proceedings of the International Symposium on Micromechatronics and Human Science. IEEE, Piscataway, NJ, United States, pp. 213-215, Proceedings of the 1998 9th International Symposium on Micromechatronics and Human Science, MHS, Nagoya, Jpn, 98/11/25.
Mikhailenko S, Sergeyev VG, Yoshikawa K. Reentrant conformational transitions in DNA molecules complexed with cationic surfactant. In Proceedings of the International Symposium on Micromechatronics and Human Science. Piscataway, NJ, United States: IEEE. 1998. p. 213-215
Mikhailenko, Sergey ; Sergeyev, V. G. ; Yoshikawa, K. / Reentrant conformational transitions in DNA molecules complexed with cationic surfactant. Proceedings of the International Symposium on Micromechatronics and Human Science. Piscataway, NJ, United States : IEEE, 1998. pp. 213-215
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