Regional differences in elements of human peroneus longustendons

Norikazu Matsumoto, Tsukasa Kumai, Shinji Isomoto, Yasushi Shinohara, Yasuhito Tanaka, Cho Azuma, Takeshi Minami, Yoshiyuki Tohno

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Many studies have been performed on the structure, molecular composition, and biochemical properties of tendons. However, comparatively little research has been conducted on the content of various trace elements within tendons. Six elements were analyzed in four regions of the peroneus longus tendon: the tensional part of the tendon immediately proximal to the lateral malleolus (region A), the compressive region of the tendon in contact with the lateral malleolus (region B), the compressive region of the tendon in contact with the deep surface of the cuboid (region C), and the tensional part of the tendon between the cuboid and first metatarsal, to which the tendon is attached (region D). Regions B and C are wraparound regions. The calcium content was higher in region C (2.10 ± 0.93 mg/g) than in both regions A (1.25 ± 0.51 mg/g) and D (1.43 ± 0.41 mg/g) (p < 0.05), indicating that it is likely related to regional differences in cartilage degeneration. The phosphorus content was also higher in region C, possibly because of low alkaline phosphatase activity in this region. The sulfur content was higher in the wraparound regions (region B: 0.98 ± 0.09 mg/g, region C: 1.24 ± 0.19 mg/g) than in both regions A (0.83 ± 0.11 mg/g) and D (0.83 ± 0.1 mg/g) (p < 0.01); sulfur content is thought to be influenced by tendon-bone compression. Finally, the magnesium content in the wraparound regions was also higher, which is probably related to a higher level of fibrocartilage. No significant relationships were found with regard to zinc or iron. Overall, the findings of the present study indicate that element contents are related to function and anatomical differences in tendons, and that they may even vary within the same tendon.

Original languageEnglish
Pages (from-to)185-189
Number of pages5
JournalBiological Trace Element Research
Volume154
Issue number2
DOIs
Publication statusPublished - 2013 Aug
Externally publishedYes

Fingerprint

Tendons
Sulfur
Fibrocartilage
Metatarsal Bones
Cartilage
Trace Elements
Molecular Structure
Phosphorus
Magnesium
Molecular structure
Alkaline Phosphatase
Zinc
Bone
Iron
Calcium
Bone and Bones

Keywords

  • Calcium
  • Peroneus longus tendon
  • Proteoglycans
  • Sulfur
  • Wraparound tendon

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Inorganic Chemistry
  • Biochemistry, medical
  • Endocrinology, Diabetes and Metabolism

Cite this

Matsumoto, N., Kumai, T., Isomoto, S., Shinohara, Y., Tanaka, Y., Azuma, C., ... Tohno, Y. (2013). Regional differences in elements of human peroneus longustendons. Biological Trace Element Research, 154(2), 185-189. https://doi.org/10.1007/s12011-013-9735-3

Regional differences in elements of human peroneus longustendons. / Matsumoto, Norikazu; Kumai, Tsukasa; Isomoto, Shinji; Shinohara, Yasushi; Tanaka, Yasuhito; Azuma, Cho; Minami, Takeshi; Tohno, Yoshiyuki.

In: Biological Trace Element Research, Vol. 154, No. 2, 08.2013, p. 185-189.

Research output: Contribution to journalArticle

Matsumoto, N, Kumai, T, Isomoto, S, Shinohara, Y, Tanaka, Y, Azuma, C, Minami, T & Tohno, Y 2013, 'Regional differences in elements of human peroneus longustendons', Biological Trace Element Research, vol. 154, no. 2, pp. 185-189. https://doi.org/10.1007/s12011-013-9735-3
Matsumoto, Norikazu ; Kumai, Tsukasa ; Isomoto, Shinji ; Shinohara, Yasushi ; Tanaka, Yasuhito ; Azuma, Cho ; Minami, Takeshi ; Tohno, Yoshiyuki. / Regional differences in elements of human peroneus longustendons. In: Biological Trace Element Research. 2013 ; Vol. 154, No. 2. pp. 185-189.
@article{0e378d9062eb4b8e9a8cad03bfc5ab56,
title = "Regional differences in elements of human peroneus longustendons",
abstract = "Many studies have been performed on the structure, molecular composition, and biochemical properties of tendons. However, comparatively little research has been conducted on the content of various trace elements within tendons. Six elements were analyzed in four regions of the peroneus longus tendon: the tensional part of the tendon immediately proximal to the lateral malleolus (region A), the compressive region of the tendon in contact with the lateral malleolus (region B), the compressive region of the tendon in contact with the deep surface of the cuboid (region C), and the tensional part of the tendon between the cuboid and first metatarsal, to which the tendon is attached (region D). Regions B and C are wraparound regions. The calcium content was higher in region C (2.10 ± 0.93 mg/g) than in both regions A (1.25 ± 0.51 mg/g) and D (1.43 ± 0.41 mg/g) (p < 0.05), indicating that it is likely related to regional differences in cartilage degeneration. The phosphorus content was also higher in region C, possibly because of low alkaline phosphatase activity in this region. The sulfur content was higher in the wraparound regions (region B: 0.98 ± 0.09 mg/g, region C: 1.24 ± 0.19 mg/g) than in both regions A (0.83 ± 0.11 mg/g) and D (0.83 ± 0.1 mg/g) (p < 0.01); sulfur content is thought to be influenced by tendon-bone compression. Finally, the magnesium content in the wraparound regions was also higher, which is probably related to a higher level of fibrocartilage. No significant relationships were found with regard to zinc or iron. Overall, the findings of the present study indicate that element contents are related to function and anatomical differences in tendons, and that they may even vary within the same tendon.",
keywords = "Calcium, Peroneus longus tendon, Proteoglycans, Sulfur, Wraparound tendon",
author = "Norikazu Matsumoto and Tsukasa Kumai and Shinji Isomoto and Yasushi Shinohara and Yasuhito Tanaka and Cho Azuma and Takeshi Minami and Yoshiyuki Tohno",
year = "2013",
month = "8",
doi = "10.1007/s12011-013-9735-3",
language = "English",
volume = "154",
pages = "185--189",
journal = "Biological Trace Element Research",
issn = "0163-4984",
publisher = "Humana Press",
number = "2",

}

TY - JOUR

T1 - Regional differences in elements of human peroneus longustendons

AU - Matsumoto, Norikazu

AU - Kumai, Tsukasa

AU - Isomoto, Shinji

AU - Shinohara, Yasushi

AU - Tanaka, Yasuhito

AU - Azuma, Cho

AU - Minami, Takeshi

AU - Tohno, Yoshiyuki

PY - 2013/8

Y1 - 2013/8

N2 - Many studies have been performed on the structure, molecular composition, and biochemical properties of tendons. However, comparatively little research has been conducted on the content of various trace elements within tendons. Six elements were analyzed in four regions of the peroneus longus tendon: the tensional part of the tendon immediately proximal to the lateral malleolus (region A), the compressive region of the tendon in contact with the lateral malleolus (region B), the compressive region of the tendon in contact with the deep surface of the cuboid (region C), and the tensional part of the tendon between the cuboid and first metatarsal, to which the tendon is attached (region D). Regions B and C are wraparound regions. The calcium content was higher in region C (2.10 ± 0.93 mg/g) than in both regions A (1.25 ± 0.51 mg/g) and D (1.43 ± 0.41 mg/g) (p < 0.05), indicating that it is likely related to regional differences in cartilage degeneration. The phosphorus content was also higher in region C, possibly because of low alkaline phosphatase activity in this region. The sulfur content was higher in the wraparound regions (region B: 0.98 ± 0.09 mg/g, region C: 1.24 ± 0.19 mg/g) than in both regions A (0.83 ± 0.11 mg/g) and D (0.83 ± 0.1 mg/g) (p < 0.01); sulfur content is thought to be influenced by tendon-bone compression. Finally, the magnesium content in the wraparound regions was also higher, which is probably related to a higher level of fibrocartilage. No significant relationships were found with regard to zinc or iron. Overall, the findings of the present study indicate that element contents are related to function and anatomical differences in tendons, and that they may even vary within the same tendon.

AB - Many studies have been performed on the structure, molecular composition, and biochemical properties of tendons. However, comparatively little research has been conducted on the content of various trace elements within tendons. Six elements were analyzed in four regions of the peroneus longus tendon: the tensional part of the tendon immediately proximal to the lateral malleolus (region A), the compressive region of the tendon in contact with the lateral malleolus (region B), the compressive region of the tendon in contact with the deep surface of the cuboid (region C), and the tensional part of the tendon between the cuboid and first metatarsal, to which the tendon is attached (region D). Regions B and C are wraparound regions. The calcium content was higher in region C (2.10 ± 0.93 mg/g) than in both regions A (1.25 ± 0.51 mg/g) and D (1.43 ± 0.41 mg/g) (p < 0.05), indicating that it is likely related to regional differences in cartilage degeneration. The phosphorus content was also higher in region C, possibly because of low alkaline phosphatase activity in this region. The sulfur content was higher in the wraparound regions (region B: 0.98 ± 0.09 mg/g, region C: 1.24 ± 0.19 mg/g) than in both regions A (0.83 ± 0.11 mg/g) and D (0.83 ± 0.1 mg/g) (p < 0.01); sulfur content is thought to be influenced by tendon-bone compression. Finally, the magnesium content in the wraparound regions was also higher, which is probably related to a higher level of fibrocartilage. No significant relationships were found with regard to zinc or iron. Overall, the findings of the present study indicate that element contents are related to function and anatomical differences in tendons, and that they may even vary within the same tendon.

KW - Calcium

KW - Peroneus longus tendon

KW - Proteoglycans

KW - Sulfur

KW - Wraparound tendon

UR - http://www.scopus.com/inward/record.url?scp=84880292414&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84880292414&partnerID=8YFLogxK

U2 - 10.1007/s12011-013-9735-3

DO - 10.1007/s12011-013-9735-3

M3 - Article

C2 - 23812651

AN - SCOPUS:84880292414

VL - 154

SP - 185

EP - 189

JO - Biological Trace Element Research

JF - Biological Trace Element Research

SN - 0163-4984

IS - 2

ER -