Reoxygenation in tumor tissues after X-ray or carbon-12 irradiation

Takeshi Fukawa; Koji Takematsu; Kotaro Oka; Nobuyuki Miyahara; Sachiko Koike; Koichi Ando; Hirosuke Kobayashi; Kazuo Tanishita

Reoxygenation in tumor tissues after X-ray or carbon-12 irradiation

Takeshi Fukawa^*, Koji Takematsu, Kotaro Oka, Nobuyuki Miyahara, Sachiko Koike, Koichi Ando, Hirosuke Kobayashi, Kazuo Tanishita

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

We measured directly the partial pressure of oxygen (pO ₂) in new fibrosarcoma (NFSa) tumors grown in C3H/He mice using microcoaxial O ₂ electrodes in vivo. The pO ₂ in tumors was monitored after a single dose of X-ray or carbon-12 irradiation. After irradiation, tumor volume temporally shrinked, and pO ₂ simultaneously increased. Carbon-12 irradiation reoxygenated tumors between the 1st and 9th day after the irradiation, while x-ray irradiation reoxygenated tumors between the 3rd and 8th day. We found that reoxygenation period after carbon-12 irradiation started earlier and continued longer than X-ray irradiation.

Original language	English
Title of host publication	American Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Pages	371-372
Number of pages	2
Volume	39
Publication status	Published - 1998
Externally published	Yes

ASJC Scopus subject areas

Engineering(all)

Cite this

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title = "Reoxygenation in tumor tissues after X-ray or carbon-12 irradiation",

abstract = "We measured directly the partial pressure of oxygen (pO 2) in new fibrosarcoma (NFSa) tumors grown in C3H/He mice using microcoaxial O 2 electrodes in vivo. The pO 2 in tumors was monitored after a single dose of X-ray or carbon-12 irradiation. After irradiation, tumor volume temporally shrinked, and pO 2 simultaneously increased. Carbon-12 irradiation reoxygenated tumors between the 1st and 9th day after the irradiation, while x-ray irradiation reoxygenated tumors between the 3rd and 8th day. We found that reoxygenation period after carbon-12 irradiation started earlier and continued longer than X-ray irradiation. ",

author = "Takeshi Fukawa and Koji Takematsu and Kotaro Oka and Nobuyuki Miyahara and Sachiko Koike and Koichi Ando and Hirosuke Kobayashi and Kazuo Tanishita",

year = "1998",

language = "English",

volume = "39",

pages = "371--372",

booktitle = "American Society of Mechanical Engineers, Bioengineering Division (Publication) BED",

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TY - CHAP

T1 - Reoxygenation in tumor tissues after X-ray or carbon-12 irradiation

AU - Fukawa, Takeshi

AU - Takematsu, Koji

AU - Oka, Kotaro

AU - Miyahara, Nobuyuki

AU - Koike, Sachiko

AU - Ando, Koichi

AU - Kobayashi, Hirosuke

AU - Tanishita, Kazuo

PY - 1998

Y1 - 1998

N2 - We measured directly the partial pressure of oxygen (pO 2) in new fibrosarcoma (NFSa) tumors grown in C3H/He mice using microcoaxial O 2 electrodes in vivo. The pO 2 in tumors was monitored after a single dose of X-ray or carbon-12 irradiation. After irradiation, tumor volume temporally shrinked, and pO 2 simultaneously increased. Carbon-12 irradiation reoxygenated tumors between the 1st and 9th day after the irradiation, while x-ray irradiation reoxygenated tumors between the 3rd and 8th day. We found that reoxygenation period after carbon-12 irradiation started earlier and continued longer than X-ray irradiation.

AB - We measured directly the partial pressure of oxygen (pO 2) in new fibrosarcoma (NFSa) tumors grown in C3H/He mice using microcoaxial O 2 electrodes in vivo. The pO 2 in tumors was monitored after a single dose of X-ray or carbon-12 irradiation. After irradiation, tumor volume temporally shrinked, and pO 2 simultaneously increased. Carbon-12 irradiation reoxygenated tumors between the 1st and 9th day after the irradiation, while x-ray irradiation reoxygenated tumors between the 3rd and 8th day. We found that reoxygenation period after carbon-12 irradiation started earlier and continued longer than X-ray irradiation.

UR - http://www.scopus.com/inward/record.url?scp=0032302996&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032302996&partnerID=8YFLogxK

M3 - Chapter

AN - SCOPUS:0032302996

VL - 39

SP - 371

EP - 372

BT - American Society of Mechanical Engineers, Bioengineering Division (Publication) BED

ER -

Reoxygenation in tumor tissues after X-ray or carbon-12 irradiation

Abstract

ASJC Scopus subject areas

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