Repulsive effects of hydrophobic diamond thin films on biomolecule detection

A. Rahim Ruslinda, Y. Ishiyama, V. Penmatsa, S. Ibori, Hiroshi Kawarada

    Research output: Contribution to journalArticle

    2 Citations (Scopus)

    Abstract

    The repulsive effect of hydrophobic diamond thin film on biomolecule detection, such as single-nucleotide polymorphisms and human immunodeficiency virus type 1 trans-activator of transcription peptide protein detection, was investigated using a mixture of a fluorine-, amine-, and hydrogen-terminated diamond surfaces. These chemical modifications lead to the formation of a surface that effectively resists the nonspecific adsorption of proteins and other biomolecules. The effect of fluorine plasma treatment on elemental composition was also investigated via X-ray photoelectron spectroscopy (XPS). XPS results revealed a fluorocarbon layer on the diamond thin films. The contact angle measurement results indicated that the fluorine-treated diamond thin films were highly hydrophobic with a surface energy value of ∼25 mN/m.

    Original languageEnglish
    Pages (from-to)314-318
    Number of pages5
    JournalApplied Surface Science
    Volume328
    DOIs
    Publication statusPublished - 2015 Feb 15

    Fingerprint

    Fluorine
    Diamond films
    Biomolecules
    Thin films
    X ray photoelectron spectroscopy
    Proteins
    Fluorocarbons
    Diamond
    Trans-Activators
    Chemical modification
    Transcription
    Angle measurement
    Nucleotides
    Polymorphism
    Viruses
    Interfacial energy
    Peptides
    Contact angle
    Amines
    Hydrogen

    Keywords

    • Biomolecules
    • Chemical modification
    • Diamond film
    • Fluorine

    ASJC Scopus subject areas

    • Surfaces, Coatings and Films

    Cite this

    Repulsive effects of hydrophobic diamond thin films on biomolecule detection. / Ruslinda, A. Rahim; Ishiyama, Y.; Penmatsa, V.; Ibori, S.; Kawarada, Hiroshi.

    In: Applied Surface Science, Vol. 328, 15.02.2015, p. 314-318.

    Research output: Contribution to journalArticle

    Ruslinda, A. Rahim ; Ishiyama, Y. ; Penmatsa, V. ; Ibori, S. ; Kawarada, Hiroshi. / Repulsive effects of hydrophobic diamond thin films on biomolecule detection. In: Applied Surface Science. 2015 ; Vol. 328. pp. 314-318.
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