Research on the design, synthesis, and catalytic activity of chiral N-heterocyclic carbene ligand-metal complexes

Kensuke Usui, Takuya Yoshida, Masahisa Nakada

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

New chiral C2 symmetric N-heterocyclic carbene (NHC) ligands with a binaphthyl backbone have been synthesized. X-ray crystallographic analysis of the new NHC-AuCl complex revealed that the phenyl groups of the binaphthyl backbone sterically regulated the direction of the nitrogen substituents of the imidazolylidene which would induce enantioselectivity in reactions. The new cationic NHC-Au(I) complexes efficiently catalyzed the cyclization of a 1,6-ene-yne and the intermediate of the cyclization was trapped by MeOH to afford the final product in high yields with up to 44% ee.

Original languageEnglish
Pages (from-to)107-113
Number of pages7
JournalTetrahedron Asymmetry
Volume27
Issue number2-3
DOIs
Publication statusPublished - 2016 Feb 15

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

Fingerprint Dive into the research topics of 'Research on the design, synthesis, and catalytic activity of chiral N-heterocyclic carbene ligand-metal complexes'. Together they form a unique fingerprint.

Cite this