Respiratory muscle strength in relation to sarcopenia in elderly cardiac patients

Kazuhiro P. Izawa, Satoshi Watanabe, Koichiro Oka, Yusuke Kasahara, Yuji Morio, Koji Hiraki, Yasuyuki Hirano, Yutaka Omori, Norio Suzuki, Keisuke Kida, Kengo Suzuki, Yoshihiro J. Akashi

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background and aims: Little information exists on the relation between respiratory muscle strength such as maximum inspiratory muscle pressure (MIP) and sarcopenia in elderly cardiac patients. The present study aimed to determine the differences in MIP, and cutoff values for MIP according to sarcopenia in elderly cardiac patients. Methods: We enrolled 63 consecutive elderly male patients aged ≥65 years with cardiac disease in this cross-sectional study. Sarcopenia was defined based on the European Working Group on Sarcopenia in Older People algorithm, and, accordingly, the patients were divided into two groups: the sarcopenia group (n = 24) and non-sarcopenia group (n = 39). The prevalence of sarcopenia in cardiac patients and MIP in the patients with and without sarcopenia were assessed to determine cutoff values of MIP. Results: After adjustment for body mass index, the MIP in the sarcopenia group was significantly lower than that in the non-sarcopenia group (54.7 ± 36.8 cmH2O; 95 % CI 42.5–72.6 vs. 80.7 ± 34.7 cmH2O; 95 % CI 69.5–92.0; F = 4.89, p = 0.029). A receiver-operating characteristic curve analysis of patients with and without sarcopenia identified a cutoff value for MIP of 55.6 cmH2O, with a sensitivity of 0.76, 1-specificity of 0.37, and AUC of 0.70 (95 % CI 0.56–0.83; p = 0.01) in the study patients. Conclusion: Compared with elderly cardiac patients without sarcopenia, MIP in those with sarcopenia may be negatively affected. The MIP cutoff value reported here may be a useful minimum target value for identifying elderly male cardiac patients with sarcopenia.

Original languageEnglish
Pages (from-to)1-6
Number of pages6
JournalAging clinical and experimental research
DOIs
Publication statusAccepted/In press - 2016 Jan 22

Fingerprint

Sarcopenia
Respiratory Muscles
Muscle Strength
Muscles
Maximal Respiratory Pressures
ROC Curve
Area Under Curve
Heart Diseases

Keywords

  • Cardiac patients
  • Elderly
  • Respiratory muscle strength
  • Sarcopenia

ASJC Scopus subject areas

  • Ageing
  • Geriatrics and Gerontology

Cite this

Respiratory muscle strength in relation to sarcopenia in elderly cardiac patients. / Izawa, Kazuhiro P.; Watanabe, Satoshi; Oka, Koichiro; Kasahara, Yusuke; Morio, Yuji; Hiraki, Koji; Hirano, Yasuyuki; Omori, Yutaka; Suzuki, Norio; Kida, Keisuke; Suzuki, Kengo; Akashi, Yoshihiro J.

In: Aging clinical and experimental research, 22.01.2016, p. 1-6.

Research output: Contribution to journalArticle

Izawa, KP, Watanabe, S, Oka, K, Kasahara, Y, Morio, Y, Hiraki, K, Hirano, Y, Omori, Y, Suzuki, N, Kida, K, Suzuki, K & Akashi, YJ 2016, 'Respiratory muscle strength in relation to sarcopenia in elderly cardiac patients', Aging clinical and experimental research, pp. 1-6. https://doi.org/10.1007/s40520-016-0534-5
Izawa, Kazuhiro P. ; Watanabe, Satoshi ; Oka, Koichiro ; Kasahara, Yusuke ; Morio, Yuji ; Hiraki, Koji ; Hirano, Yasuyuki ; Omori, Yutaka ; Suzuki, Norio ; Kida, Keisuke ; Suzuki, Kengo ; Akashi, Yoshihiro J. / Respiratory muscle strength in relation to sarcopenia in elderly cardiac patients. In: Aging clinical and experimental research. 2016 ; pp. 1-6.
@article{7ce4d9f73b8d429caab67255d5d4c71c,
title = "Respiratory muscle strength in relation to sarcopenia in elderly cardiac patients",
abstract = "Background and aims: Little information exists on the relation between respiratory muscle strength such as maximum inspiratory muscle pressure (MIP) and sarcopenia in elderly cardiac patients. The present study aimed to determine the differences in MIP, and cutoff values for MIP according to sarcopenia in elderly cardiac patients. Methods: We enrolled 63 consecutive elderly male patients aged ≥65 years with cardiac disease in this cross-sectional study. Sarcopenia was defined based on the European Working Group on Sarcopenia in Older People algorithm, and, accordingly, the patients were divided into two groups: the sarcopenia group (n = 24) and non-sarcopenia group (n = 39). The prevalence of sarcopenia in cardiac patients and MIP in the patients with and without sarcopenia were assessed to determine cutoff values of MIP. Results: After adjustment for body mass index, the MIP in the sarcopenia group was significantly lower than that in the non-sarcopenia group (54.7 ± 36.8 cmH2O; 95 {\%} CI 42.5–72.6 vs. 80.7 ± 34.7 cmH2O; 95 {\%} CI 69.5–92.0; F = 4.89, p = 0.029). A receiver-operating characteristic curve analysis of patients with and without sarcopenia identified a cutoff value for MIP of 55.6 cmH2O, with a sensitivity of 0.76, 1-specificity of 0.37, and AUC of 0.70 (95 {\%} CI 0.56–0.83; p = 0.01) in the study patients. Conclusion: Compared with elderly cardiac patients without sarcopenia, MIP in those with sarcopenia may be negatively affected. The MIP cutoff value reported here may be a useful minimum target value for identifying elderly male cardiac patients with sarcopenia.",
keywords = "Cardiac patients, Elderly, Respiratory muscle strength, Sarcopenia",
author = "Izawa, {Kazuhiro P.} and Satoshi Watanabe and Koichiro Oka and Yusuke Kasahara and Yuji Morio and Koji Hiraki and Yasuyuki Hirano and Yutaka Omori and Norio Suzuki and Keisuke Kida and Kengo Suzuki and Akashi, {Yoshihiro J.}",
year = "2016",
month = "1",
day = "22",
doi = "10.1007/s40520-016-0534-5",
language = "English",
pages = "1--6",
journal = "Aging clinical and experimental research",
issn = "1594-0667",
publisher = "Springer Verlag",

}

TY - JOUR

T1 - Respiratory muscle strength in relation to sarcopenia in elderly cardiac patients

AU - Izawa, Kazuhiro P.

AU - Watanabe, Satoshi

AU - Oka, Koichiro

AU - Kasahara, Yusuke

AU - Morio, Yuji

AU - Hiraki, Koji

AU - Hirano, Yasuyuki

AU - Omori, Yutaka

AU - Suzuki, Norio

AU - Kida, Keisuke

AU - Suzuki, Kengo

AU - Akashi, Yoshihiro J.

PY - 2016/1/22

Y1 - 2016/1/22

N2 - Background and aims: Little information exists on the relation between respiratory muscle strength such as maximum inspiratory muscle pressure (MIP) and sarcopenia in elderly cardiac patients. The present study aimed to determine the differences in MIP, and cutoff values for MIP according to sarcopenia in elderly cardiac patients. Methods: We enrolled 63 consecutive elderly male patients aged ≥65 years with cardiac disease in this cross-sectional study. Sarcopenia was defined based on the European Working Group on Sarcopenia in Older People algorithm, and, accordingly, the patients were divided into two groups: the sarcopenia group (n = 24) and non-sarcopenia group (n = 39). The prevalence of sarcopenia in cardiac patients and MIP in the patients with and without sarcopenia were assessed to determine cutoff values of MIP. Results: After adjustment for body mass index, the MIP in the sarcopenia group was significantly lower than that in the non-sarcopenia group (54.7 ± 36.8 cmH2O; 95 % CI 42.5–72.6 vs. 80.7 ± 34.7 cmH2O; 95 % CI 69.5–92.0; F = 4.89, p = 0.029). A receiver-operating characteristic curve analysis of patients with and without sarcopenia identified a cutoff value for MIP of 55.6 cmH2O, with a sensitivity of 0.76, 1-specificity of 0.37, and AUC of 0.70 (95 % CI 0.56–0.83; p = 0.01) in the study patients. Conclusion: Compared with elderly cardiac patients without sarcopenia, MIP in those with sarcopenia may be negatively affected. The MIP cutoff value reported here may be a useful minimum target value for identifying elderly male cardiac patients with sarcopenia.

AB - Background and aims: Little information exists on the relation between respiratory muscle strength such as maximum inspiratory muscle pressure (MIP) and sarcopenia in elderly cardiac patients. The present study aimed to determine the differences in MIP, and cutoff values for MIP according to sarcopenia in elderly cardiac patients. Methods: We enrolled 63 consecutive elderly male patients aged ≥65 years with cardiac disease in this cross-sectional study. Sarcopenia was defined based on the European Working Group on Sarcopenia in Older People algorithm, and, accordingly, the patients were divided into two groups: the sarcopenia group (n = 24) and non-sarcopenia group (n = 39). The prevalence of sarcopenia in cardiac patients and MIP in the patients with and without sarcopenia were assessed to determine cutoff values of MIP. Results: After adjustment for body mass index, the MIP in the sarcopenia group was significantly lower than that in the non-sarcopenia group (54.7 ± 36.8 cmH2O; 95 % CI 42.5–72.6 vs. 80.7 ± 34.7 cmH2O; 95 % CI 69.5–92.0; F = 4.89, p = 0.029). A receiver-operating characteristic curve analysis of patients with and without sarcopenia identified a cutoff value for MIP of 55.6 cmH2O, with a sensitivity of 0.76, 1-specificity of 0.37, and AUC of 0.70 (95 % CI 0.56–0.83; p = 0.01) in the study patients. Conclusion: Compared with elderly cardiac patients without sarcopenia, MIP in those with sarcopenia may be negatively affected. The MIP cutoff value reported here may be a useful minimum target value for identifying elderly male cardiac patients with sarcopenia.

KW - Cardiac patients

KW - Elderly

KW - Respiratory muscle strength

KW - Sarcopenia

UR - http://www.scopus.com/inward/record.url?scp=84955258958&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84955258958&partnerID=8YFLogxK

U2 - 10.1007/s40520-016-0534-5

DO - 10.1007/s40520-016-0534-5

M3 - Article

SP - 1

EP - 6

JO - Aging clinical and experimental research

JF - Aging clinical and experimental research

SN - 1594-0667

ER -