Resting-state brain activity in the motor cortex reflects task-induced activity: A multi-voxel pattern analysis

Toshiki Kusano, Hiroki Kurashige, Isao Nambu, Yoshiya Moriguchi, Takashi Hanakawa, Yasuhiro Wada, Rieko Osu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

It has been suggested that resting-state brain activity reflects task-induced brain activity patterns. In this study, we examined whether neural representations of specific movements can be observed in the resting-state brain activity patterns of motor areas. First, we defined two regions of interest (ROIs) to examine brain activity associated with two different behavioral tasks. Using multi-voxel pattern analysis with regularized logistic regression, we designed a decoder to detect voxel-level neural representations corresponding to the tasks in each ROI. Next, we applied the decoder to resting-state brain activity. We found that the decoder discriminated resting-state neural activity with accuracy comparable to that associated with task-induced neural activity. The distribution of learned weighted parameters for each ROI was similar for resting-state and task-induced activities. Large weighted parameters were mainly located on conjunctive areas. Moreover, the accuracy of detection was higher than that for a decoder whose weights were randomly shuffled, indicating that the resting-state brain activity includes multi-voxel patterns similar to the neural representation for the tasks. Therefore, these results suggest that the neural representation of resting-state brain activity is more finely organized and more complex than conventionally considered.

Original languageEnglish
Title of host publication2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages4290-4293
Number of pages4
Volume2015-November
ISBN (Electronic)9781424492718
DOIs
Publication statusPublished - 2015 Nov 4
Externally publishedYes
Event37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 - Milan, Italy
Duration: 2015 Aug 252015 Aug 29

Other

Other37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
CountryItaly
CityMilan
Period15/8/2515/8/29

Fingerprint

Motor Cortex
Brain
Logistics
Logistic Models
Weights and Measures

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

Cite this

Kusano, T., Kurashige, H., Nambu, I., Moriguchi, Y., Hanakawa, T., Wada, Y., & Osu, R. (2015). Resting-state brain activity in the motor cortex reflects task-induced activity: A multi-voxel pattern analysis. In 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 (Vol. 2015-November, pp. 4290-4293). [7319343] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2015.7319343

Resting-state brain activity in the motor cortex reflects task-induced activity : A multi-voxel pattern analysis. / Kusano, Toshiki; Kurashige, Hiroki; Nambu, Isao; Moriguchi, Yoshiya; Hanakawa, Takashi; Wada, Yasuhiro; Osu, Rieko.

2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Vol. 2015-November Institute of Electrical and Electronics Engineers Inc., 2015. p. 4290-4293 7319343.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kusano, T, Kurashige, H, Nambu, I, Moriguchi, Y, Hanakawa, T, Wada, Y & Osu, R 2015, Resting-state brain activity in the motor cortex reflects task-induced activity: A multi-voxel pattern analysis. in 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. vol. 2015-November, 7319343, Institute of Electrical and Electronics Engineers Inc., pp. 4290-4293, 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015, Milan, Italy, 15/8/25. https://doi.org/10.1109/EMBC.2015.7319343
Kusano T, Kurashige H, Nambu I, Moriguchi Y, Hanakawa T, Wada Y et al. Resting-state brain activity in the motor cortex reflects task-induced activity: A multi-voxel pattern analysis. In 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Vol. 2015-November. Institute of Electrical and Electronics Engineers Inc. 2015. p. 4290-4293. 7319343 https://doi.org/10.1109/EMBC.2015.7319343
Kusano, Toshiki ; Kurashige, Hiroki ; Nambu, Isao ; Moriguchi, Yoshiya ; Hanakawa, Takashi ; Wada, Yasuhiro ; Osu, Rieko. / Resting-state brain activity in the motor cortex reflects task-induced activity : A multi-voxel pattern analysis. 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Vol. 2015-November Institute of Electrical and Electronics Engineers Inc., 2015. pp. 4290-4293
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