Rheological property of artificial red cells suspended in plasma expanders (water soluble polymers)

Atsushi Satoh; Hiromi Sakai; Shinji Takeoka; Eishun Tsuchida

Rheological property of artificial red cells suspended in plasma expanders (water soluble polymers)

Atsushi Satoh^*, Hiromi Sakai, Shinji Takeoka, Eishun Tsuchida

^*Corresponding author for this work

School of Advanced Science and Engineering

Research output: Contribution to conference › Paper › peer-review

Abstract

Hemoglobin-vesicles (HbVs) are developed as artificial red cells. The HbV suspension does not have a detectable colloid osmotic pressure. Therefore, the intravenous infusion of large amount of HbV requires an addition of a plasma expander (e.g., albumin, polysaccharides, or gelatin solution). Here, we analyzed the viscoelastic property of these suspensions. In the case of HbVs suspended in albumin, the viscoelastic property showed approximately Newtonian. Other suspensions showed shear thinning due to reversible aggregation of HbVs induced by the interaction with the plasma expanders.

Original language	English
Number of pages	1
Publication status	Published - 2006 Oct 19
Event	55th SPSJ Annual Meeting - Nagoya, Japan Duration: 2006 May 24 → 2006 May 26

Conference

Conference	55th SPSJ Annual Meeting
Country/Territory	Japan
City	Nagoya
Period	06/5/24 → 06/5/26

Keywords

Artificial red cell
Hemorheology
Liposome
Plasma expander
Polyethylene glycol

ASJC Scopus subject areas

Engineering(all)

Cite this

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title = "Rheological property of artificial red cells suspended in plasma expanders (water soluble polymers)",

abstract = "Hemoglobin-vesicles (HbVs) are developed as artificial red cells. The HbV suspension does not have a detectable colloid osmotic pressure. Therefore, the intravenous infusion of large amount of HbV requires an addition of a plasma expander (e.g., albumin, polysaccharides, or gelatin solution). Here, we analyzed the viscoelastic property of these suspensions. In the case of HbVs suspended in albumin, the viscoelastic property showed approximately Newtonian. Other suspensions showed shear thinning due to reversible aggregation of HbVs induced by the interaction with the plasma expanders.",

keywords = "Artificial red cell, Hemorheology, Liposome, Plasma expander, Polyethylene glycol",

author = "Atsushi Satoh and Hiromi Sakai and Shinji Takeoka and Eishun Tsuchida",

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day = "19",

language = "English",

note = "55th SPSJ Annual Meeting ; Conference date: 24-05-2006 Through 26-05-2006",

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T1 - Rheological property of artificial red cells suspended in plasma expanders (water soluble polymers)

AU - Satoh, Atsushi

AU - Sakai, Hiromi

AU - Takeoka, Shinji

AU - Tsuchida, Eishun

PY - 2006/10/19

Y1 - 2006/10/19

N2 - Hemoglobin-vesicles (HbVs) are developed as artificial red cells. The HbV suspension does not have a detectable colloid osmotic pressure. Therefore, the intravenous infusion of large amount of HbV requires an addition of a plasma expander (e.g., albumin, polysaccharides, or gelatin solution). Here, we analyzed the viscoelastic property of these suspensions. In the case of HbVs suspended in albumin, the viscoelastic property showed approximately Newtonian. Other suspensions showed shear thinning due to reversible aggregation of HbVs induced by the interaction with the plasma expanders.

AB - Hemoglobin-vesicles (HbVs) are developed as artificial red cells. The HbV suspension does not have a detectable colloid osmotic pressure. Therefore, the intravenous infusion of large amount of HbV requires an addition of a plasma expander (e.g., albumin, polysaccharides, or gelatin solution). Here, we analyzed the viscoelastic property of these suspensions. In the case of HbVs suspended in albumin, the viscoelastic property showed approximately Newtonian. Other suspensions showed shear thinning due to reversible aggregation of HbVs induced by the interaction with the plasma expanders.

KW - Artificial red cell

KW - Hemorheology

KW - Liposome

KW - Plasma expander

KW - Polyethylene glycol

UR - http://www.scopus.com/inward/record.url?scp=33749824930&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33749824930&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:33749824930

T2 - 55th SPSJ Annual Meeting

Y2 - 24 May 2006 through 26 May 2006

ER -

Rheological property of artificial red cells suspended in plasma expanders (water soluble polymers)

Abstract

Conference

Keywords

ASJC Scopus subject areas

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