Rheological property of artificial red cells suspended in plasma expanders (water soluble polymers)

Atsushi Satoh, Hiromi Sakai, Shinji Takeoka, Eishun Tsuchida

Research output: Contribution to conferencePaperpeer-review

Abstract

Hemoglobin-vesicles (HbVs) are developed as artificial red cells. The HbV suspension does not have a detectable colloid osmotic pressure. Therefore, the intravenous infusion of large amount of HbV requires an addition of a plasma expander (e.g., albumin, polysaccharides, or gelatin solution). Here, we analyzed the viscoelastic property of these suspensions. In the case of HbVs suspended in albumin, the viscoelastic property showed approximately Newtonian. Other suspensions showed shear thinning due to reversible aggregation of HbVs induced by the interaction with the plasma expanders.

Original languageEnglish
Number of pages1
Publication statusPublished - 2006 Oct 19
Event55th SPSJ Annual Meeting - Nagoya, Japan
Duration: 2006 May 242006 May 26

Conference

Conference55th SPSJ Annual Meeting
CountryJapan
CityNagoya
Period06/5/2406/5/26

Keywords

  • Artificial red cell
  • Hemorheology
  • Liposome
  • Plasma expander
  • Polyethylene glycol

ASJC Scopus subject areas

  • Engineering(all)

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