Rhodium-catalyzed enantioselective [2+2+2] cycloaddition of diynes with unfunctionalized alkenes

Takanori Shibata, Ai Kawachi, Mika Ogawa, Yusuke Kuwata, Kyoji Tsuchikama, Kohei Endo

    Research output: Contribution to journalArticle

    33 Citations (Scopus)

    Abstract

    A chiral rhodium complex catalyzed an enantioselective [2+2+2] cycloaddition of unsymmetrical diynes with norbornene, and tetracyclic products were obtained in good to excellent ee. The cycloaddition of a symmetrical diyne with styrene derivatives as coupling partners gave bicyclic products in good ee.

    Original languageEnglish
    Pages (from-to)12853-12859
    Number of pages7
    JournalTetrahedron
    Volume63
    Issue number52
    DOIs
    Publication statusPublished - 2007 Dec 24

    Fingerprint

    Diynes
    Rhodium
    Cycloaddition
    Cycloaddition Reaction
    Alkenes
    Styrene
    Derivatives

    Keywords

    • Cycloaddition
    • Enantioselective
    • Norbornene
    • Rhodium
    • Styrene

    ASJC Scopus subject areas

    • Biochemistry
    • Organic Chemistry
    • Drug Discovery

    Cite this

    Rhodium-catalyzed enantioselective [2+2+2] cycloaddition of diynes with unfunctionalized alkenes. / Shibata, Takanori; Kawachi, Ai; Ogawa, Mika; Kuwata, Yusuke; Tsuchikama, Kyoji; Endo, Kohei.

    In: Tetrahedron, Vol. 63, No. 52, 24.12.2007, p. 12853-12859.

    Research output: Contribution to journalArticle

    Shibata, Takanori ; Kawachi, Ai ; Ogawa, Mika ; Kuwata, Yusuke ; Tsuchikama, Kyoji ; Endo, Kohei. / Rhodium-catalyzed enantioselective [2+2+2] cycloaddition of diynes with unfunctionalized alkenes. In: Tetrahedron. 2007 ; Vol. 63, No. 52. pp. 12853-12859.
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    AU - Tsuchikama, Kyoji

    AU - Endo, Kohei

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