RNA aptamers to a protease, subtilisin.

H. Takeno, T. Tanaka, Yo Kikuchi

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

RNA ligands (RNA aptamers) to a protease subtilisin were selected from pools of random RNA using SELEX (Systematic evolution of ligands by exponential enrichment). We selected RNA aptamers using a subtilisin-immobilized Sepharose column. After several rounds of selection, we obtained RNA aptamers that specifically inhibit the subtilisin activity. Characterization of the RNA aptamers will be reported.

Original languageEnglish
Pages (from-to)249-250
Number of pages2
JournalNucleic acids symposium series
Issue number37
Publication statusPublished - 1997
Externally publishedYes

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Nucleotide Aptamers
Subtilisin
Peptide Hydrolases
SELEX Aptamer Technique
RNA
Sepharose
Ligands

Cite this

Takeno, H., Tanaka, T., & Kikuchi, Y. (1997). RNA aptamers to a protease, subtilisin. Nucleic acids symposium series, (37), 249-250.

RNA aptamers to a protease, subtilisin. / Takeno, H.; Tanaka, T.; Kikuchi, Yo.

In: Nucleic acids symposium series, No. 37, 1997, p. 249-250.

Research output: Contribution to journalArticle

Takeno, H, Tanaka, T & Kikuchi, Y 1997, 'RNA aptamers to a protease, subtilisin.', Nucleic acids symposium series, no. 37, pp. 249-250.
Takeno H, Tanaka T, Kikuchi Y. RNA aptamers to a protease, subtilisin. Nucleic acids symposium series. 1997;(37):249-250.
Takeno, H. ; Tanaka, T. ; Kikuchi, Yo. / RNA aptamers to a protease, subtilisin. In: Nucleic acids symposium series. 1997 ; No. 37. pp. 249-250.
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