RNA Study Using DNA Nanotechnology

Hisashi Tadakuma*, Takeya Masubuchi, Takuya Ueda

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter


Transcription is one of the fundamental steps of gene expression, where RNA polymerases (RNAPs) bind to their template genes and make RNAs. In addition to RNAP and the template gene, many molecules such as transcription factors are involved. The interaction and the effect of these factors depend on the geometry. Molecular layout of these factors, RNAP and gene is thus important. DNA nanotechnology is a promising technology that allows controlling of the molecular layout in the range of nanometer to micrometer scale with nanometer resolution; thus, it is expected to expand the RNA study beyond the current limit.

Original languageEnglish
Title of host publicationNanotechnology Tools for the Study of RNA
EditorsSatoko Yoshizawa
PublisherElsevier B.V.
Number of pages43
ISBN (Print)9780128045657
Publication statusPublished - 2016
Externally publishedYes

Publication series

NameProgress in Molecular Biology and Translational Science
ISSN (Print)1877-1173
ISSN (Electronic)1878-0814


  • DNA nanostructure
  • DNA origami
  • RNA polymerase
  • atomic force microscopy (AFM)
  • single-molecule imaging

ASJC Scopus subject areas

  • Molecular Medicine
  • Molecular Biology


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