Salivary cortisol and DHEA reactivity to psychosocial stress in socially anxious males

Kentaro Shirotsuki, Shuhei Izawa, Nagisa Sugaya, Kosuke Chris Yamada, Namiko Ogawa, Yuko Ouchi, Yuichiro Nagano, Shinobu Nomura

    Research output: Contribution to journalArticle

    44 Citations (Scopus)

    Abstract

    The purpose of the present study was to examine Hypothalamus-Pituitary-Adrenal (HPA) axis reactivity in social anxiety. The present study used a standardized psychosocial stress protocol (the Trier Social Stress Test; TSST; [Kirschbaum, C., Pirke, K.M., Hellhammer, D.H., 1993. The 'Trier Social Stress Test'-a tool for investigating psychobiological stress responses in a laboratory setting. Neuropsychobiology 28, 76-81.]) with 11 higher-social-anxiety and 11 lower-social-anxiety male college students. Psychological responses and salivary cortisol and dehydroepiandrosterone (DHEA) reactivity and cortisol/DHEA ratio were assessed at seven different times. The results showed that there was a significantly lower cortisol responsiveness in the higher social anxiety group but there was no significant difference of DHEA responsiveness. Further analyses showed lower responses for the cortisol/DHEA ratio in the higher-social-anxiety group to the TSST. These results suggest that there may be reduced HPA axis reactivity to psychosocial stress in socially anxious people.

    Original languageEnglish
    Pages (from-to)198-203
    Number of pages6
    JournalInternational Journal of Psychophysiology
    Volume72
    Issue number2
    DOIs
    Publication statusPublished - 2009 May

    Fingerprint

    Dehydroepiandrosterone
    Hydrocortisone
    Anxiety
    Exercise Test
    Hypothalamus
    Students
    Psychology

    Keywords

    • Cortisol
    • Dehydroepiandrosterone
    • HPA axis
    • Social anxiety disorder
    • Trier Social Stress Test

    ASJC Scopus subject areas

    • Neuroscience(all)
    • Physiology (medical)
    • Neuropsychology and Physiological Psychology

    Cite this

    Shirotsuki, K., Izawa, S., Sugaya, N., Yamada, K. C., Ogawa, N., Ouchi, Y., ... Nomura, S. (2009). Salivary cortisol and DHEA reactivity to psychosocial stress in socially anxious males. International Journal of Psychophysiology, 72(2), 198-203. https://doi.org/10.1016/j.ijpsycho.2008.12.010

    Salivary cortisol and DHEA reactivity to psychosocial stress in socially anxious males. / Shirotsuki, Kentaro; Izawa, Shuhei; Sugaya, Nagisa; Yamada, Kosuke Chris; Ogawa, Namiko; Ouchi, Yuko; Nagano, Yuichiro; Nomura, Shinobu.

    In: International Journal of Psychophysiology, Vol. 72, No. 2, 05.2009, p. 198-203.

    Research output: Contribution to journalArticle

    Shirotsuki, K, Izawa, S, Sugaya, N, Yamada, KC, Ogawa, N, Ouchi, Y, Nagano, Y & Nomura, S 2009, 'Salivary cortisol and DHEA reactivity to psychosocial stress in socially anxious males', International Journal of Psychophysiology, vol. 72, no. 2, pp. 198-203. https://doi.org/10.1016/j.ijpsycho.2008.12.010
    Shirotsuki, Kentaro ; Izawa, Shuhei ; Sugaya, Nagisa ; Yamada, Kosuke Chris ; Ogawa, Namiko ; Ouchi, Yuko ; Nagano, Yuichiro ; Nomura, Shinobu. / Salivary cortisol and DHEA reactivity to psychosocial stress in socially anxious males. In: International Journal of Psychophysiology. 2009 ; Vol. 72, No. 2. pp. 198-203.
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