Salmonella Electrode for Screening Mutagens

Isao Karube*, Takashi Nakahara, Tadashi Matsunaga, Shuichi Suzuki

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

46 Citations (Scopus)


Preliminary screening of mutagens was completed within 10 h by using a microbial electrode system composed of an oxygen electrode and a membrane filter retaining Salmonella typhimurium revertant. The current decrease was correlated with mutagen concentrations. The minimum measurable concentration for AF-2 was 0.001 µg mL-1. The microbial electrode system was applied to the detection of other chemical mutagens such as N-methyl-N'-nitro-N-nitrosoguanidine, nltrofurazone methyl methanesulfonate, and ethyl methanesulfonate.

Original languageEnglish
Pages (from-to)1725-1727
Number of pages3
JournalAnalytical Chemistry
Issue number11
Publication statusPublished - 1982
Externally publishedYes

ASJC Scopus subject areas

  • Analytical Chemistry


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