Salmonella Electrode for Screening Mutagens

Isao Karube; Takashi Nakahara; Tadashi Matsunaga; Shuichi Suzuki

doi:10.1021/ac00248a015

Salmonella Electrode for Screening Mutagens

Isao Karube^*, Takashi Nakahara, Tadashi Matsunaga, Shuichi Suzuki

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

46 Citations (Scopus)

Abstract

Preliminary screening of mutagens was completed within 10 h by using a microbial electrode system composed of an oxygen electrode and a membrane filter retaining Salmonella typhimurium revertant. The current decrease was correlated with mutagen concentrations. The minimum measurable concentration for AF-2 was 0.001 µg mL^-1. The microbial electrode system was applied to the detection of other chemical mutagens such as N-methyl-N'-nitro-N-nitrosoguanidine, nltrofurazone methyl methanesulfonate, and ethyl methanesulfonate.

Original language	English
Pages (from-to)	1725-1727
Number of pages	3
Journal	Analytical Chemistry
Volume	54
Issue number	11
DOIs	https://doi.org/10.1021/ac00248a015
Publication status	Published - 1982
Externally published	Yes

ASJC Scopus subject areas

Analytical Chemistry

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title = "Salmonella Electrode for Screening Mutagens",

abstract = "Preliminary screening of mutagens was completed within 10 h by using a microbial electrode system composed of an oxygen electrode and a membrane filter retaining Salmonella typhimurium revertant. The current decrease was correlated with mutagen concentrations. The minimum measurable concentration for AF-2 was 0.001 µg mL-1. The microbial electrode system was applied to the detection of other chemical mutagens such as N-methyl-N'-nitro-N-nitrosoguanidine, nltrofurazone methyl methanesulfonate, and ethyl methanesulfonate.",

author = "Isao Karube and Takashi Nakahara and Tadashi Matsunaga and Shuichi Suzuki",

year = "1982",

doi = "10.1021/ac00248a015",

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T1 - Salmonella Electrode for Screening Mutagens

AU - Karube, Isao

AU - Nakahara, Takashi

AU - Matsunaga, Tadashi

AU - Suzuki, Shuichi

PY - 1982

Y1 - 1982

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AB - Preliminary screening of mutagens was completed within 10 h by using a microbial electrode system composed of an oxygen electrode and a membrane filter retaining Salmonella typhimurium revertant. The current decrease was correlated with mutagen concentrations. The minimum measurable concentration for AF-2 was 0.001 µg mL-1. The microbial electrode system was applied to the detection of other chemical mutagens such as N-methyl-N'-nitro-N-nitrosoguanidine, nltrofurazone methyl methanesulfonate, and ethyl methanesulfonate.

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Salmonella Electrode for Screening Mutagens

Abstract

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