Salt intake and mental distress among rural community-dwelling Japanese men

Yuji Shimizu, Koichiro Kadota, Jun Koyamatsu, Hirotomo Yamanashi, Mako Nagayoshi, Miki Noda, Takayuki Nishimura, Jun Tayama, Yasuhiro Nagata, Takahiro Maeda

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: Activated mineralocorticoid receptors influence the association between daily salt intake and blood pressure. A relatively low mineralocorticoid receptor function is reported to be a risk for mental distress such as depression. Since mental distress is also a known risk for hypertension and cardiovascular disease, understanding of the association between estimated daily salt intake and mental distress contributing to hypertension is important for risk estimation for cardiovascular disease. However, no single study has reported this association. Methods: We conducted a cross-sectional study of 1014 Japanese men undergoing general health check-ups. Mental distress was diagnosed as a Kessler 6 scale score ≥5. We also classified mental distress by levels of hypertension. Estimated daily salt intake was calculated from a causal urine specimen. Results: Independent from classical cardiovascular risk factors and thyroid disease, we found a significant inverse association between estimated daily salt intake and mental distress. When we analyzed for mental distress and hypertension, we also found a significant association. With the reference group being the lowest tertiles of estimated daily salt intake, the multivariable odds ratios (ORs) of mental distress and mental distress with hypertension for the highest tertiles were 0.50 (0.29-0.88) and 0.46 (0.22-0.96). Conclusions: Lower estimated daily salt intake is a significant risk of mental distress for rural community-dwelling Japanese men. Since depression is reported to be associated with cardiovascular disease, risk estimation for the lower intake of salt on mental distress, especially for mental distress with hypertension, may become an important tool to prevent cardiovascular disease.

Original languageEnglish
Article number26
JournalJournal of physiological anthropology
Volume34
Issue number1
DOIs
Publication statusPublished - 2015 Jun 25
Externally publishedYes

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Independent Living
Rural Population
hypertension
rural community
Salts
Hypertension
Disease
Cardiovascular Diseases
Mineralocorticoid Receptors
reference group
cross-sectional study
Thyroid Diseases
Blood pressure
Cross-Sectional Studies
Odds Ratio
Health
Urine
Blood Pressure
health

ASJC Scopus subject areas

  • Human Factors and Ergonomics
  • Physiology
  • Orthopedics and Sports Medicine
  • Anthropology
  • Public Health, Environmental and Occupational Health
  • Physiology (medical)

Cite this

Shimizu, Y., Kadota, K., Koyamatsu, J., Yamanashi, H., Nagayoshi, M., Noda, M., ... Maeda, T. (2015). Salt intake and mental distress among rural community-dwelling Japanese men. Journal of physiological anthropology, 34(1), [26]. https://doi.org/10.1186/s40101-015-0064-4

Salt intake and mental distress among rural community-dwelling Japanese men. / Shimizu, Yuji; Kadota, Koichiro; Koyamatsu, Jun; Yamanashi, Hirotomo; Nagayoshi, Mako; Noda, Miki; Nishimura, Takayuki; Tayama, Jun; Nagata, Yasuhiro; Maeda, Takahiro.

In: Journal of physiological anthropology, Vol. 34, No. 1, 26, 25.06.2015.

Research output: Contribution to journalArticle

Shimizu, Y, Kadota, K, Koyamatsu, J, Yamanashi, H, Nagayoshi, M, Noda, M, Nishimura, T, Tayama, J, Nagata, Y & Maeda, T 2015, 'Salt intake and mental distress among rural community-dwelling Japanese men', Journal of physiological anthropology, vol. 34, no. 1, 26. https://doi.org/10.1186/s40101-015-0064-4
Shimizu, Yuji ; Kadota, Koichiro ; Koyamatsu, Jun ; Yamanashi, Hirotomo ; Nagayoshi, Mako ; Noda, Miki ; Nishimura, Takayuki ; Tayama, Jun ; Nagata, Yasuhiro ; Maeda, Takahiro. / Salt intake and mental distress among rural community-dwelling Japanese men. In: Journal of physiological anthropology. 2015 ; Vol. 34, No. 1.
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