TY - JOUR
T1 - Secondary-electron-bremsstrahlung imaging for proton therapy
AU - Yamaguchi, Mitsutaka
AU - Nagao, Yuto
AU - Ando, Koki
AU - Yamamoto, Seiichi
AU - Toshito, Toshiyuki
AU - Kataoka, Jun
AU - Kawachi, Naoki
N1 - Funding Information:
We would like to thank the clinical team at the Nagoya Proton Therapy Center for allowing beam time for our experiments, and thank all of the staff that helped us prepare and carry out the irradiations. We also would like to thank the development members of PHITS for kind supports for our frequent questions. This work was partly supported by a Grant-in-Aid for Scientific Research (No. 15K01349 ) from the Ministry of Education, Culture, Sports, Science and Technology , Japan (MEXT). We greatly appreciate this support.
Publisher Copyright:
© 2016 Elsevier B.V.
PY - 2016/10/11
Y1 - 2016/10/11
N2 - A feasibility study on an imaging technique of a therapeutic proton-beam trajectory using a gamma camera by measuring secondary electron bremsstrahlung (SEB) was performed by means of Monte Carlo simulations and a beam-irradiation experiment. From the simulation and experimental results, it was found that a significant amount of SEB yield exists between the beam-injection surface and the range position along the beam axis and the beam trajectory is clearly imaged by the SEB yield. It is concluded that the SEB imaging is a promising technique for monitoring of therapeutic proton-beam trajectories.
AB - A feasibility study on an imaging technique of a therapeutic proton-beam trajectory using a gamma camera by measuring secondary electron bremsstrahlung (SEB) was performed by means of Monte Carlo simulations and a beam-irradiation experiment. From the simulation and experimental results, it was found that a significant amount of SEB yield exists between the beam-injection surface and the range position along the beam axis and the beam trajectory is clearly imaged by the SEB yield. It is concluded that the SEB imaging is a promising technique for monitoring of therapeutic proton-beam trajectories.
KW - Beam-trajectory imaging
KW - Gamma camera
KW - Monte Carlo simulation
KW - Proton therapy
KW - Secondary electron bremsstrahlung
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U2 - 10.1016/j.nima.2016.07.034
DO - 10.1016/j.nima.2016.07.034
M3 - Article
AN - SCOPUS:84990059040
VL - 833
SP - 199
EP - 207
JO - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
JF - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
SN - 0168-9002
ER -