Selective detection and transport of fully matched DNA by DNA-loaded microtubule and kinesin motor protein

Shu Taira; Yong Zhong Du; Yuichi Hiratsuka; Kaoru Konishi; Tai Kubo; Taro Q.P. Uyeda; Noboru Yumoto; Masato Kodaka

doi:10.1002/bit.21055

Selective detection and transport of fully matched DNA by DNA-loaded microtubule and kinesin motor protein

Shu Taira, Yong Zhong Du, Yuichi Hiratsuka, Kaoru Konishi, Tai Kubo, Taro Q.P. Uyeda, Noboru Yumoto, Masato Kodaka^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

49 Citations (Scopus)

Abstract

DNA-loaded microtubules (MTs) moving on a kinesin motor protein-coated substrate can selectively hybridize with a target fully matched DNA over single-base mismatched DNA and transport it. This technique is capable of collecting target biomolecules toward one point site to design new methodology of DNA analysis.

Original language	English
Pages (from-to)	533-538
Number of pages	6
Journal	Biotechnology and bioengineering
Volume	95
Issue number	3
DOIs	https://doi.org/10.1002/bit.21055
Publication status	Published - 2006 Oct 20
Externally published	Yes

Keywords

DNA-loaded microtubules
Motor protein
SNP

ASJC Scopus subject areas

Biotechnology
Bioengineering
Applied Microbiology and Biotechnology

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10.1002/bit.21055

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Selective detection and transport of fully matched DNA by DNA-loaded microtubule and kinesin motor protein. / Taira, Shu; Du, Yong Zhong; Hiratsuka, Yuichi; Konishi, Kaoru; Kubo, Tai; Uyeda, Taro Q.P.; Yumoto, Noboru; Kodaka, Masato.

In: Biotechnology and bioengineering, Vol. 95, No. 3, 20.10.2006, p. 533-538.

Research output: Contribution to journal › Article › peer-review

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abstract = "DNA-loaded microtubules (MTs) moving on a kinesin motor protein-coated substrate can selectively hybridize with a target fully matched DNA over single-base mismatched DNA and transport it. This technique is capable of collecting target biomolecules toward one point site to design new methodology of DNA analysis.",

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AU - Taira, Shu

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AU - Hiratsuka, Yuichi

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AU - Kubo, Tai

AU - Uyeda, Taro Q.P.

AU - Yumoto, Noboru

AU - Kodaka, Masato

PY - 2006/10/20

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AB - DNA-loaded microtubules (MTs) moving on a kinesin motor protein-coated substrate can selectively hybridize with a target fully matched DNA over single-base mismatched DNA and transport it. This technique is capable of collecting target biomolecules toward one point site to design new methodology of DNA analysis.

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Selective detection and transport of fully matched DNA by DNA-loaded microtubule and kinesin motor protein

Abstract

Keywords

ASJC Scopus subject areas

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