Abstract
DNA-loaded microtubules (MTs) moving on a kinesin motor protein-coated substrate can selectively hybridize with a target fully matched DNA over single-base mismatched DNA and transport it. This technique is capable of collecting target biomolecules toward one point site to design new methodology of DNA analysis.
| Original language | English |
|---|---|
| Pages (from-to) | 533-538 |
| Number of pages | 6 |
| Journal | Biotechnology and bioengineering |
| Volume | 95 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2006 Oct 20 |
| Externally published | Yes |
Keywords
- DNA-loaded microtubules
- Motor protein
- SNP
ASJC Scopus subject areas
- Biotechnology
- Bioengineering
- Applied Microbiology and Biotechnology
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Cite this
Taira, S., Du, Y. Z., Hiratsuka, Y., Konishi, K., Kubo, T., Uyeda, T. Q. P., Yumoto, N., & Kodaka, M. (2006). Selective detection and transport of fully matched DNA by DNA-loaded microtubule and kinesin motor protein. Biotechnology and bioengineering, 95(3), 533-538. https://doi.org/10.1002/bit.21055