Self-healing polyurethane elastomers based on charge-transfer interactions for biomedical applications

Keiichi Imato*, Hidekazu Nakajima, Ryota Yamanaka, Naoya Takeda

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)


One promising application of self-healing polymeric materials is biomedical use. Although charge-transfer (CT) interactions have been employed to construct self-healing polymers as well as other reversible bonds and interactions, their potential for biomedical applications has never been investigated. In this study, we fabricated self-healable and cell-compatible polyurethane elastomers cross-linked by CT complexes between electron-rich pyrene (Py) and electron-deficient naphthalene diimide (NDI) by simply blending two linear polymers with Py or NDI as a repeating unit. The elastomers with different blend ratios self-healed damage over 1 day in mild conditions, including in air and water at 30–100 °C. The mechanical properties of damaged elastomers were almost restored after healing in air at 100 °C, and even in air at 30 °C and in water at 70 °C, healing was also possible to a certain extent. The good cell compatibility of the polyurethane elastomers was demonstrated by culturing two kinds of cells on the thin film substrates.

Original languageEnglish
Pages (from-to)355-362
Number of pages8
JournalPolymer Journal
Issue number2
Publication statusPublished - 2021 Feb

ASJC Scopus subject areas

  • Polymers and Plastics
  • Materials Chemistry


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