Separation of non-spherical biological cells with center of gravity offset by a shear flow

Fumihiko Mikami, Kazuo Tanishita

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The numerical simulation of cell movement in a shear flow is performed to propose a new cell sorting method using a dumbbell model which describes non-spherical biological cells with center of gravity offset. A dumbbell is found to rotate or glide, depending on the center of gravity offset and the strength of shear flow. In rotating motion, the dumbbell rotates and falls vertically, accompanied by a periodical horizontal drift. In gliding motion, the dumbbell orients and glides in a fluid, where the gliding angle is determined by the center of gravity offset.

Original languageEnglish
Title of host publicationAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
EditorsM.C. Boyce
Place of PublicationNew York, NY, United States
PublisherASME
Pages263-264
Number of pages2
Volume31
Publication statusPublished - 1995
Externally publishedYes
EventProceedings of the 1995 ASME International Mechanical Congress and Exposition - San Francisco, CA, USA
Duration: 1995 Nov 121995 Nov 17

Other

OtherProceedings of the 1995 ASME International Mechanical Congress and Exposition
CitySan Francisco, CA, USA
Period95/11/1295/11/17

ASJC Scopus subject areas

  • Engineering(all)

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  • Cite this

    Mikami, F., & Tanishita, K. (1995). Separation of non-spherical biological cells with center of gravity offset by a shear flow. In M. C. Boyce (Ed.), American Society of Mechanical Engineers, Bioengineering Division (Publication) BED (Vol. 31, pp. 263-264). ASME.