Shape-memory surface with dynamically tunable nano-geometry activated by body heat

Mitsuhiro Ebara; Koichiro Uto; Naokazu Idota; John M. Hoffman; Takao Aoyagi

doi:10.1002/adma.201102181

Shape-memory surface with dynamically tunable nano-geometry activated by body heat

Mitsuhiro Ebara, Koichiro Uto, Naokazu Idota, John M. Hoffman, Takao Aoyagi^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

161 Citations (Scopus)

Abstract

Shape-memory surfaces with on-demand, tunable nanopatterns are developed to observe time dependent changes in cell alignment using temperature-responsive poly(Ïμ-caprolactone) (PCL) films. Temporary grooved nanopatterns are easily programmed on the films and triggered to transition quickly to permanent surface patterns by the application of body heat. A time-dependent cytoskeleton remodeling is also observed under biologically relevant conditions.

Original language	English
Pages (from-to)	273-278
Number of pages	6
Journal	Advanced Materials
Volume	24
Issue number	2
DOIs	https://doi.org/10.1002/adma.201102181
Publication status	Published - 2012 Jan 10
Externally published	Yes

Keywords

biomedical applications
polymeric materials
shape-memory materials
stimuli-responsive materials

ASJC Scopus subject areas

Materials Science(all)
Mechanics of Materials
Mechanical Engineering

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10.1002/adma.201102181

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abstract = "Shape-memory surfaces with on-demand, tunable nanopatterns are developed to observe time dependent changes in cell alignment using temperature-responsive poly({\"I}μ-caprolactone) (PCL) films. Temporary grooved nanopatterns are easily programmed on the films and triggered to transition quickly to permanent surface patterns by the application of body heat. A time-dependent cytoskeleton remodeling is also observed under biologically relevant conditions.",

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AU - Ebara, Mitsuhiro

AU - Uto, Koichiro

AU - Idota, Naokazu

AU - Hoffman, John M.

AU - Aoyagi, Takao

PY - 2012/1/10

Y1 - 2012/1/10

N2 - Shape-memory surfaces with on-demand, tunable nanopatterns are developed to observe time dependent changes in cell alignment using temperature-responsive poly(Ïμ-caprolactone) (PCL) films. Temporary grooved nanopatterns are easily programmed on the films and triggered to transition quickly to permanent surface patterns by the application of body heat. A time-dependent cytoskeleton remodeling is also observed under biologically relevant conditions.

AB - Shape-memory surfaces with on-demand, tunable nanopatterns are developed to observe time dependent changes in cell alignment using temperature-responsive poly(Ïμ-caprolactone) (PCL) films. Temporary grooved nanopatterns are easily programmed on the films and triggered to transition quickly to permanent surface patterns by the application of body heat. A time-dependent cytoskeleton remodeling is also observed under biologically relevant conditions.

KW - biomedical applications

KW - polymeric materials

KW - shape-memory materials

KW - stimuli-responsive materials

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ER -

Shape-memory surface with dynamically tunable nano-geometry activated by body heat

Abstract

Keywords

ASJC Scopus subject areas

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