Silicon intake to vertebral columns of mice after dietary supply

Atsuko Izu, Tsukasa Kumai, Yoshiyuki Tohno, Setsuko Tohno, Takeshi Minami, Gen Yamada, Masa Oki Yamada

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Vertebral columns were dissected and analyzed after birth with oral administration of silicon for 4 wk and for 8 wk. The silicon level was lower (20 μg/g) at the beginning. It remains unchanged after 4 wk and then increases twice as much as that for those mice bred for 8 wk than those bred for 4 wk. This increase depends remarkably on the mass ratio of Si/Ca (M/M). The ratio increases to three times higher than that of the control at the beginning of the experiments (5 wk after birth). Although the S and P contents appeared to be lower, these increased when Si was administered in combination with phosphopeptide. Other elements, such as Ca, Mg, Fe, and Zn, appeared to be unchanged as the weeks proceeded. These findings seem to support a proposal that silicon is necessary for the growth of backbones in mice.

Original languageEnglish
Pages (from-to)297-316
Number of pages20
JournalBiological Trace Element Research
Volume113
Issue number3
DOIs
Publication statusPublished - 2006 Dec
Externally publishedYes

Fingerprint

Silicon
Spine
Parturition
Phosphopeptides
Oral Administration
Growth
Experiments

Keywords

  • Backbone
  • Bone
  • Mouse vertebra
  • Si
  • Si intake
  • Silicon

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Clinical Biochemistry
  • Biochemistry, medical
  • Inorganic Chemistry

Cite this

Izu, A., Kumai, T., Tohno, Y., Tohno, S., Minami, T., Yamada, G., & Yamada, M. O. (2006). Silicon intake to vertebral columns of mice after dietary supply. Biological Trace Element Research, 113(3), 297-316. https://doi.org/10.1385/BTER:113:3:297

Silicon intake to vertebral columns of mice after dietary supply. / Izu, Atsuko; Kumai, Tsukasa; Tohno, Yoshiyuki; Tohno, Setsuko; Minami, Takeshi; Yamada, Gen; Yamada, Masa Oki.

In: Biological Trace Element Research, Vol. 113, No. 3, 12.2006, p. 297-316.

Research output: Contribution to journalArticle

Izu, A, Kumai, T, Tohno, Y, Tohno, S, Minami, T, Yamada, G & Yamada, MO 2006, 'Silicon intake to vertebral columns of mice after dietary supply', Biological Trace Element Research, vol. 113, no. 3, pp. 297-316. https://doi.org/10.1385/BTER:113:3:297
Izu, Atsuko ; Kumai, Tsukasa ; Tohno, Yoshiyuki ; Tohno, Setsuko ; Minami, Takeshi ; Yamada, Gen ; Yamada, Masa Oki. / Silicon intake to vertebral columns of mice after dietary supply. In: Biological Trace Element Research. 2006 ; Vol. 113, No. 3. pp. 297-316.
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