Skeletal muscle deoxygenation responses during treadmill exercise in children

Shun Takagi, Ryotaro Kime, Taishi Midorikawa, Masatsugu Niwayama, Shizuo Sakamoto, Toshihito Katsumura

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Muscle O2 saturation (SmO2) and blood volume response in activating muscles during treadmill exercise were compared between prepubertal boys (n = 9, age: 9 ± 1 years) and young men (n = 9, age: 22 ± 2 years). SmO2 and blood volume responses were monitored continuously during the exercise at the gastrocnemius medialis muscle by near infrared spatial resolved spectroscopy. SmO2 was significantly decreased only at peak exercise in the boys, even though a significant decrease in SmO2 was observed at 60, 80, and 100% of peak O2 uptake in the men (p < 0.05). No significant increase in blood volume was observed in the boys, while blood volume was significantly increased in the men with increased exercise intensity (p < 0.05). These results suggest that both blood volume and deoxygenation response in activating muscle may be minor in prepubertal boys, compared to young men. The blunted deoxygenation response in prepubertal boys may be caused by undeveloped diffusive O2 transport (i.e. mitochondrial respiration).

Original languageEnglish
Pages (from-to)341-346
Number of pages6
JournalAdvances in Experimental Medicine and Biology
Volume812
DOIs
Publication statusPublished - 2014

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Exercise equipment
Muscle
Skeletal Muscle
Blood
Exercise
Blood Volume
Muscles
Spectroscopy
Infrared radiation
Spectrum Analysis
Respiration

Keywords

  • Blood volume
  • Muscle oxygen saturation
  • Near-infrared spatial resolved spectroscopy
  • Prepubertal boys
  • Young men

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Skeletal muscle deoxygenation responses during treadmill exercise in children. / Takagi, Shun; Kime, Ryotaro; Midorikawa, Taishi; Niwayama, Masatsugu; Sakamoto, Shizuo; Katsumura, Toshihito.

In: Advances in Experimental Medicine and Biology, Vol. 812, 2014, p. 341-346.

Research output: Contribution to journalArticle

Takagi, Shun ; Kime, Ryotaro ; Midorikawa, Taishi ; Niwayama, Masatsugu ; Sakamoto, Shizuo ; Katsumura, Toshihito. / Skeletal muscle deoxygenation responses during treadmill exercise in children. In: Advances in Experimental Medicine and Biology. 2014 ; Vol. 812. pp. 341-346.
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