TY - JOUR
T1 - Skeletal muscle deoxygenation responses during treadmill exercise in children
AU - Takagi, Shun
AU - Kime, Ryotaro
AU - Midorikawa, Taishi
AU - Niwayama, Masatsugu
AU - Sakamoto, Shizuo
AU - Katsumura, Toshihito
N1 - Publisher Copyright:
© Springer Science+Business Media, LLC 2014.
PY - 2014
Y1 - 2014
N2 - Muscle O2 saturation (SmO2) and blood volume response in activating muscles during treadmill exercise were compared between prepubertal boys (n = 9, age: 9 ± 1 years) and young men (n = 9, age: 22 ± 2 years). SmO2 and blood volume responses were monitored continuously during the exercise at the gastrocnemius medialis muscle by near infrared spatial resolved spectroscopy. SmO2 was significantly decreased only at peak exercise in the boys, even though a significant decrease in SmO2 was observed at 60, 80, and 100% of peak O2 uptake in the men (p < 0.05). No significant increase in blood volume was observed in the boys, while blood volume was significantly increased in the men with increased exercise intensity (p < 0.05). These results suggest that both blood volume and deoxygenation response in activating muscle may be minor in prepubertal boys, compared to young men. The blunted deoxygenation response in prepubertal boys may be caused by undeveloped diffusive O2 transport (i.e. mitochondrial respiration).
AB - Muscle O2 saturation (SmO2) and blood volume response in activating muscles during treadmill exercise were compared between prepubertal boys (n = 9, age: 9 ± 1 years) and young men (n = 9, age: 22 ± 2 years). SmO2 and blood volume responses were monitored continuously during the exercise at the gastrocnemius medialis muscle by near infrared spatial resolved spectroscopy. SmO2 was significantly decreased only at peak exercise in the boys, even though a significant decrease in SmO2 was observed at 60, 80, and 100% of peak O2 uptake in the men (p < 0.05). No significant increase in blood volume was observed in the boys, while blood volume was significantly increased in the men with increased exercise intensity (p < 0.05). These results suggest that both blood volume and deoxygenation response in activating muscle may be minor in prepubertal boys, compared to young men. The blunted deoxygenation response in prepubertal boys may be caused by undeveloped diffusive O2 transport (i.e. mitochondrial respiration).
KW - Blood volume
KW - Muscle oxygen saturation
KW - Near-infrared spatial resolved spectroscopy
KW - Prepubertal boys
KW - Young men
UR - http://www.scopus.com/inward/record.url?scp=84905909562&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84905909562&partnerID=8YFLogxK
U2 - 10.1007/978-1-4939-0620-8_45
DO - 10.1007/978-1-4939-0620-8_45
M3 - Article
C2 - 24729252
AN - SCOPUS:84905909562
SN - 0065-2598
VL - 812
SP - 341
EP - 346
JO - Advances in Experimental Medicine and Biology
JF - Advances in Experimental Medicine and Biology
ER -