Sleep quality under mild hypoxia in men with low hypoxic ventilatory response

Masako Hoshikawa, Sunao Uchida, Masashi Ganeko, Junya Sumitomo, Masatsugu Totoki, Takuto Kojima, Yukiko Nakamura, Takashi Kawahara

    Research output: Contribution to journalArticle

    2 Citations (Scopus)

    Abstract

    The present study evaluated whether slow-wave sleep and whole-night delta power of the non-rapid eye movement (NREM) sleep electroencephalogram (EEG) decrease during sleep at a simulated altitude of 2000 m, and whether such changes related to measures of hypoxic ventilatory response (HVR). This study consisted of two parts; in the first, HVR was measured in 41 subjects and each seven subjects with the lowest or the highest HVR were selected for the subsequent sleep study. In the second part, polysomnogram, arterial oxygen saturation (SpO2) and respiratory events are recorded on the selected subjects under normoxic and hypoxic conditions. Hypoxia decreased SpO2 and increased respiratory disturbances for both groups. The low HVR group, but not the high HVR group, showed decreases in the whole-night delta power of NREM sleep EEG under hypoxia. On the other hand, two subjects in the high HVR group, who showed relatively high apnoea indices, also showed lower SpO2 nadirs and decreases in the whole-night delta power under hypoxia. These results suggest that acute hypoxia equivalent to that at a 2000 m altitude decreases slow-wave sleep in individuals that show low HVR. However, low HVR may not be the only, but one of some factors that decrease the whole-night delta power under hypoxia. Therefore, it was not sufficient to identify individuals likely to be susceptible to deteriorated sleep quality at a simulated altitude of 2000 m only using the HVR test. Other factors, which relate to respiratory instabilities, should be taken into consideration to identify them.

    Original languageEnglish
    JournalEuropean Journal of Sport Science
    Volume14
    Issue numberSUPPL.1
    DOIs
    Publication statusPublished - 2014 Jan

    Fingerprint

    Sleep
    Eye Movements
    Electroencephalography
    Apnea
    Hypoxia
    Oxygen
    Power (Psychology)

    Keywords

    • Normobaric hypoxia
    • polysomnography
    • slow-wave sleep
    • ventilatory chemosensitivity

    ASJC Scopus subject areas

    • Physical Therapy, Sports Therapy and Rehabilitation
    • Orthopedics and Sports Medicine

    Cite this

    Hoshikawa, M., Uchida, S., Ganeko, M., Sumitomo, J., Totoki, M., Kojima, T., ... Kawahara, T. (2014). Sleep quality under mild hypoxia in men with low hypoxic ventilatory response. European Journal of Sport Science, 14(SUPPL.1). https://doi.org/10.1080/17461391.2012.681805

    Sleep quality under mild hypoxia in men with low hypoxic ventilatory response. / Hoshikawa, Masako; Uchida, Sunao; Ganeko, Masashi; Sumitomo, Junya; Totoki, Masatsugu; Kojima, Takuto; Nakamura, Yukiko; Kawahara, Takashi.

    In: European Journal of Sport Science, Vol. 14, No. SUPPL.1, 01.2014.

    Research output: Contribution to journalArticle

    Hoshikawa, M, Uchida, S, Ganeko, M, Sumitomo, J, Totoki, M, Kojima, T, Nakamura, Y & Kawahara, T 2014, 'Sleep quality under mild hypoxia in men with low hypoxic ventilatory response', European Journal of Sport Science, vol. 14, no. SUPPL.1. https://doi.org/10.1080/17461391.2012.681805
    Hoshikawa, Masako ; Uchida, Sunao ; Ganeko, Masashi ; Sumitomo, Junya ; Totoki, Masatsugu ; Kojima, Takuto ; Nakamura, Yukiko ; Kawahara, Takashi. / Sleep quality under mild hypoxia in men with low hypoxic ventilatory response. In: European Journal of Sport Science. 2014 ; Vol. 14, No. SUPPL.1.
    @article{cc63796e3158444bb9f58ab263c800cf,
    title = "Sleep quality under mild hypoxia in men with low hypoxic ventilatory response",
    abstract = "The present study evaluated whether slow-wave sleep and whole-night delta power of the non-rapid eye movement (NREM) sleep electroencephalogram (EEG) decrease during sleep at a simulated altitude of 2000 m, and whether such changes related to measures of hypoxic ventilatory response (HVR). This study consisted of two parts; in the first, HVR was measured in 41 subjects and each seven subjects with the lowest or the highest HVR were selected for the subsequent sleep study. In the second part, polysomnogram, arterial oxygen saturation (SpO2) and respiratory events are recorded on the selected subjects under normoxic and hypoxic conditions. Hypoxia decreased SpO2 and increased respiratory disturbances for both groups. The low HVR group, but not the high HVR group, showed decreases in the whole-night delta power of NREM sleep EEG under hypoxia. On the other hand, two subjects in the high HVR group, who showed relatively high apnoea indices, also showed lower SpO2 nadirs and decreases in the whole-night delta power under hypoxia. These results suggest that acute hypoxia equivalent to that at a 2000 m altitude decreases slow-wave sleep in individuals that show low HVR. However, low HVR may not be the only, but one of some factors that decrease the whole-night delta power under hypoxia. Therefore, it was not sufficient to identify individuals likely to be susceptible to deteriorated sleep quality at a simulated altitude of 2000 m only using the HVR test. Other factors, which relate to respiratory instabilities, should be taken into consideration to identify them.",
    keywords = "Normobaric hypoxia, polysomnography, slow-wave sleep, ventilatory chemosensitivity",
    author = "Masako Hoshikawa and Sunao Uchida and Masashi Ganeko and Junya Sumitomo and Masatsugu Totoki and Takuto Kojima and Yukiko Nakamura and Takashi Kawahara",
    year = "2014",
    month = "1",
    doi = "10.1080/17461391.2012.681805",
    language = "English",
    volume = "14",
    journal = "European Journal of Sport Science",
    issn = "1746-1391",
    publisher = "Taylor and Francis Ltd.",
    number = "SUPPL.1",

    }

    TY - JOUR

    T1 - Sleep quality under mild hypoxia in men with low hypoxic ventilatory response

    AU - Hoshikawa, Masako

    AU - Uchida, Sunao

    AU - Ganeko, Masashi

    AU - Sumitomo, Junya

    AU - Totoki, Masatsugu

    AU - Kojima, Takuto

    AU - Nakamura, Yukiko

    AU - Kawahara, Takashi

    PY - 2014/1

    Y1 - 2014/1

    N2 - The present study evaluated whether slow-wave sleep and whole-night delta power of the non-rapid eye movement (NREM) sleep electroencephalogram (EEG) decrease during sleep at a simulated altitude of 2000 m, and whether such changes related to measures of hypoxic ventilatory response (HVR). This study consisted of two parts; in the first, HVR was measured in 41 subjects and each seven subjects with the lowest or the highest HVR were selected for the subsequent sleep study. In the second part, polysomnogram, arterial oxygen saturation (SpO2) and respiratory events are recorded on the selected subjects under normoxic and hypoxic conditions. Hypoxia decreased SpO2 and increased respiratory disturbances for both groups. The low HVR group, but not the high HVR group, showed decreases in the whole-night delta power of NREM sleep EEG under hypoxia. On the other hand, two subjects in the high HVR group, who showed relatively high apnoea indices, also showed lower SpO2 nadirs and decreases in the whole-night delta power under hypoxia. These results suggest that acute hypoxia equivalent to that at a 2000 m altitude decreases slow-wave sleep in individuals that show low HVR. However, low HVR may not be the only, but one of some factors that decrease the whole-night delta power under hypoxia. Therefore, it was not sufficient to identify individuals likely to be susceptible to deteriorated sleep quality at a simulated altitude of 2000 m only using the HVR test. Other factors, which relate to respiratory instabilities, should be taken into consideration to identify them.

    AB - The present study evaluated whether slow-wave sleep and whole-night delta power of the non-rapid eye movement (NREM) sleep electroencephalogram (EEG) decrease during sleep at a simulated altitude of 2000 m, and whether such changes related to measures of hypoxic ventilatory response (HVR). This study consisted of two parts; in the first, HVR was measured in 41 subjects and each seven subjects with the lowest or the highest HVR were selected for the subsequent sleep study. In the second part, polysomnogram, arterial oxygen saturation (SpO2) and respiratory events are recorded on the selected subjects under normoxic and hypoxic conditions. Hypoxia decreased SpO2 and increased respiratory disturbances for both groups. The low HVR group, but not the high HVR group, showed decreases in the whole-night delta power of NREM sleep EEG under hypoxia. On the other hand, two subjects in the high HVR group, who showed relatively high apnoea indices, also showed lower SpO2 nadirs and decreases in the whole-night delta power under hypoxia. These results suggest that acute hypoxia equivalent to that at a 2000 m altitude decreases slow-wave sleep in individuals that show low HVR. However, low HVR may not be the only, but one of some factors that decrease the whole-night delta power under hypoxia. Therefore, it was not sufficient to identify individuals likely to be susceptible to deteriorated sleep quality at a simulated altitude of 2000 m only using the HVR test. Other factors, which relate to respiratory instabilities, should be taken into consideration to identify them.

    KW - Normobaric hypoxia

    KW - polysomnography

    KW - slow-wave sleep

    KW - ventilatory chemosensitivity

    UR - http://www.scopus.com/inward/record.url?scp=84893088731&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=84893088731&partnerID=8YFLogxK

    U2 - 10.1080/17461391.2012.681805

    DO - 10.1080/17461391.2012.681805

    M3 - Article

    C2 - 24444208

    AN - SCOPUS:84893088731

    VL - 14

    JO - European Journal of Sport Science

    JF - European Journal of Sport Science

    SN - 1746-1391

    IS - SUPPL.1

    ER -