Small, soft, and safe microactuator for retinal pigment epithelium transplantation

Yusaku Watanabe, Masanori Maeda, Naoko Yaji, Ryoichi Nakamura, Hiroshi Iseki, Masayuki Yamato, Teruo Okano, Sadao Hori, Satoshi Konishi

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    50 Citations (Scopus)

    Abstract

    This paper proposes a novel surgical tool for the Retinal Pigment Epithelium (RPE) sheet transplantation. The proposed tool employs the principle of pneumatic balloon actuator (PBA). It is possible to design small, soft and safe surgical tool by using PBA because PBA is made of PDMS and driven by pneumatic pressure. These distinctive characteristics of PBA are attractive for such a challenging surgery as the RPE sheet transplantation in an eyeball. The designed head size of tool is 3mm × 3mm × 10μm by taking account of the size of the RPE sheet (3mm × 3mm). The developed tool can perform sequential motions through independent control of different PBA so as to introduce and transplant the RPE sheet to an eyeball. Generated force by the movement of the transplantation tool is measured around 3mN, which is allowable in an eyeball. Experimental results of both in vitro and in vivo test by using the developed tool will be reported to demonstrate feasibility of our strategy.

    Original languageEnglish
    Title of host publicationProceedings - CIS Workshops 2007, 2007 International Conference on Computational Intelligence and Security Workshops, CISW 2007
    Pages659-662
    Number of pages4
    Publication statusPublished - 2007 Dec 1
    Event20th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2007 - Kobe, Japan
    Duration: 2007 Jan 212007 Jan 25

    Publication series

    NameProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
    ISSN (Print)1084-6999

    Conference

    Conference20th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2007
    CountryJapan
    CityKobe
    Period07/1/2107/1/25

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Condensed Matter Physics
    • Mechanical Engineering
    • Electrical and Electronic Engineering

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  • Cite this

    Watanabe, Y., Maeda, M., Yaji, N., Nakamura, R., Iseki, H., Yamato, M., Okano, T., Hori, S., & Konishi, S. (2007). Small, soft, and safe microactuator for retinal pigment epithelium transplantation. In Proceedings - CIS Workshops 2007, 2007 International Conference on Computational Intelligence and Security Workshops, CISW 2007 (pp. 659-662). [4433083] (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).