Small, soft, and safe microactuator for retinal pigment epithelium transplantation

Yusaku Watanabe, Masanori Maeda, Naoko Yaji, Ryoichi Nakamura, Hiroshi Iseki, Masayuki Yamato, Teruo Okano, Sadao Hori, Satoshi Konishi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

46 Citations (Scopus)

Abstract

This paper proposes a novel surgical tool for the Retinal Pigment Epithelium (RPE) sheet transplantation. The proposed tool employs the principle of pneumatic balloon actuator (PBA). It is possible to design small, soft and safe surgical tool by using PBA because PBA is made of PDMS and driven by pneumatic pressure. These distinctive characteristics of PBA are attractive for such a challenging surgery as the RPE sheet transplantation in an eyeball. The designed head size of tool is 3mm × 3mm × 10μm by taking account of the size of the RPE sheet (3mm × 3mm). The developed tool can perform sequential motions through independent control of different PBA so as to introduce and transplant the RPE sheet to an eyeball. Generated force by the movement of the transplantation tool is measured around 3mN, which is allowable in an eyeball. Experimental results of both in vitro and in vivo test by using the developed tool will be reported to demonstrate feasibility of our strategy.

Original languageEnglish
Title of host publicationProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Pages659-662
Number of pages4
Publication statusPublished - 2007
Externally publishedYes
Event20th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2007 - Kobe
Duration: 2007 Jan 212007 Jan 25

Other

Other20th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2007
CityKobe
Period07/1/2107/1/25

Fingerprint

Microactuators
transplantation
Retinal Pigments
epithelium
pigments
pneumatics
Pigments
Balloons
balloons
Pneumatics
actuators
Actuators
Pneumatic actuators
Transplants
surgery
Surgery

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Mechanical Engineering
  • Condensed Matter Physics
  • Electronic, Optical and Magnetic Materials

Cite this

Watanabe, Y., Maeda, M., Yaji, N., Nakamura, R., Iseki, H., Yamato, M., ... Konishi, S. (2007). Small, soft, and safe microactuator for retinal pigment epithelium transplantation. In Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) (pp. 659-662). [4433083]

Small, soft, and safe microactuator for retinal pigment epithelium transplantation. / Watanabe, Yusaku; Maeda, Masanori; Yaji, Naoko; Nakamura, Ryoichi; Iseki, Hiroshi; Yamato, Masayuki; Okano, Teruo; Hori, Sadao; Konishi, Satoshi.

Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). 2007. p. 659-662 4433083.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Watanabe, Y, Maeda, M, Yaji, N, Nakamura, R, Iseki, H, Yamato, M, Okano, T, Hori, S & Konishi, S 2007, Small, soft, and safe microactuator for retinal pigment epithelium transplantation. in Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)., 4433083, pp. 659-662, 20th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2007, Kobe, 07/1/21.
Watanabe Y, Maeda M, Yaji N, Nakamura R, Iseki H, Yamato M et al. Small, soft, and safe microactuator for retinal pigment epithelium transplantation. In Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). 2007. p. 659-662. 4433083
Watanabe, Yusaku ; Maeda, Masanori ; Yaji, Naoko ; Nakamura, Ryoichi ; Iseki, Hiroshi ; Yamato, Masayuki ; Okano, Teruo ; Hori, Sadao ; Konishi, Satoshi. / Small, soft, and safe microactuator for retinal pigment epithelium transplantation. Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). 2007. pp. 659-662
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