Spatiotemporal control of migration of single cells arrayed on a caged cell-culturing substrate

Jun Nakanishi, Yukiko Kikuchi, Satoshi Inoue, Kazuo Yamaguchi, Tohru Takarada, Mizuo Maeda

Research output: Contribution to conferencePaper

Abstract

Spatiotemporal control of cell protrusions and migration were achieved on a photoactivatable cell-culturing substrate. Single cells were micropatterned on the substrate and were induced to extend lamellipodia or filopodia alternatively by the subsequent formation of wide or narrow paths in their surroundings, respectively. By tracking the migration of individual cells in a microarray format, we demonstrated that the cell migration led by lamellipodia was more rapid than that led by filopodia.

Original languageEnglish
Number of pages1
Publication statusPublished - 2006 Dec 1
Externally publishedYes
Event55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan
Duration: 2006 Sep 202006 Sep 22

Other

Other55th Society of Polymer Science Japan Symposium on Macromolecules
CountryJapan
CityToyama
Period06/9/2006/9/22

Fingerprint

Cells
Substrates
Microarrays

Keywords

  • Caged compounds
  • Cell adhesion
  • Cell array
  • Cell migration
  • Monolayer

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Nakanishi, J., Kikuchi, Y., Inoue, S., Yamaguchi, K., Takarada, T., & Maeda, M. (2006). Spatiotemporal control of migration of single cells arrayed on a caged cell-culturing substrate. Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan.

Spatiotemporal control of migration of single cells arrayed on a caged cell-culturing substrate. / Nakanishi, Jun; Kikuchi, Yukiko; Inoue, Satoshi; Yamaguchi, Kazuo; Takarada, Tohru; Maeda, Mizuo.

2006. Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan.

Research output: Contribution to conferencePaper

Nakanishi, J, Kikuchi, Y, Inoue, S, Yamaguchi, K, Takarada, T & Maeda, M 2006, 'Spatiotemporal control of migration of single cells arrayed on a caged cell-culturing substrate' Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan, 06/9/20 - 06/9/22, .
Nakanishi J, Kikuchi Y, Inoue S, Yamaguchi K, Takarada T, Maeda M. Spatiotemporal control of migration of single cells arrayed on a caged cell-culturing substrate. 2006. Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan.
Nakanishi, Jun ; Kikuchi, Yukiko ; Inoue, Satoshi ; Yamaguchi, Kazuo ; Takarada, Tohru ; Maeda, Mizuo. / Spatiotemporal control of migration of single cells arrayed on a caged cell-culturing substrate. Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan.1 p.
@conference{0c3e540649a44a1da7695a0b4f0fd6b3,
title = "Spatiotemporal control of migration of single cells arrayed on a caged cell-culturing substrate",
abstract = "Spatiotemporal control of cell protrusions and migration were achieved on a photoactivatable cell-culturing substrate. Single cells were micropatterned on the substrate and were induced to extend lamellipodia or filopodia alternatively by the subsequent formation of wide or narrow paths in their surroundings, respectively. By tracking the migration of individual cells in a microarray format, we demonstrated that the cell migration led by lamellipodia was more rapid than that led by filopodia.",
keywords = "Caged compounds, Cell adhesion, Cell array, Cell migration, Monolayer",
author = "Jun Nakanishi and Yukiko Kikuchi and Satoshi Inoue and Kazuo Yamaguchi and Tohru Takarada and Mizuo Maeda",
year = "2006",
month = "12",
day = "1",
language = "English",
note = "55th Society of Polymer Science Japan Symposium on Macromolecules ; Conference date: 20-09-2006 Through 22-09-2006",

}

TY - CONF

T1 - Spatiotemporal control of migration of single cells arrayed on a caged cell-culturing substrate

AU - Nakanishi, Jun

AU - Kikuchi, Yukiko

AU - Inoue, Satoshi

AU - Yamaguchi, Kazuo

AU - Takarada, Tohru

AU - Maeda, Mizuo

PY - 2006/12/1

Y1 - 2006/12/1

N2 - Spatiotemporal control of cell protrusions and migration were achieved on a photoactivatable cell-culturing substrate. Single cells were micropatterned on the substrate and were induced to extend lamellipodia or filopodia alternatively by the subsequent formation of wide or narrow paths in their surroundings, respectively. By tracking the migration of individual cells in a microarray format, we demonstrated that the cell migration led by lamellipodia was more rapid than that led by filopodia.

AB - Spatiotemporal control of cell protrusions and migration were achieved on a photoactivatable cell-culturing substrate. Single cells were micropatterned on the substrate and were induced to extend lamellipodia or filopodia alternatively by the subsequent formation of wide or narrow paths in their surroundings, respectively. By tracking the migration of individual cells in a microarray format, we demonstrated that the cell migration led by lamellipodia was more rapid than that led by filopodia.

KW - Caged compounds

KW - Cell adhesion

KW - Cell array

KW - Cell migration

KW - Monolayer

UR - http://www.scopus.com/inward/record.url?scp=33846131988&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846131988&partnerID=8YFLogxK

M3 - Paper

ER -