Spatiotemporal control of migration of single cells arrayed on a caged cell-culturing substrate

Jun Nakanishi, Yukiko Kikuchi, Satoshi Inoue, Kazuo Yamaguchi, Tohru Takarada, Mizuo Maeda

Research output: Contribution to conferencePaperpeer-review

Abstract

Spatiotemporal control of cell protrusions and migration were achieved on a photoactivatable cell-culturing substrate. Single cells were micropatterned on the substrate and were induced to extend lamellipodia or filopodia alternatively by the subsequent formation of wide or narrow paths in their surroundings, respectively. By tracking the migration of individual cells in a microarray format, we demonstrated that the cell migration led by lamellipodia was more rapid than that led by filopodia.

Original languageEnglish
Pages4861
Number of pages1
Publication statusPublished - 2006
Externally publishedYes
Event55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan
Duration: 2006 Sep 202006 Sep 22

Other

Other55th Society of Polymer Science Japan Symposium on Macromolecules
Country/TerritoryJapan
CityToyama
Period06/9/2006/9/22

Keywords

  • Caged compounds
  • Cell adhesion
  • Cell array
  • Cell migration
  • Monolayer

ASJC Scopus subject areas

  • Engineering(all)

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