Stability of porphyrin-calix[4]arene complexes analyzed by electrospray ionization mass spectrometry

Satoshi Arai, Shinsuke Ishihara, Shinji Takeoka, Haruki Ohkawa, Toshimichi Shibue, Hiroyuki Nishide

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

The stability of some porphyrin-calix[4]arene sodium-ion complexes were determined by a collision-activated decomposition (CAD) method utilizing electrospray ionization mass spectrometry (ESI-MS). Comparing the values of E1/2, the collision energy at which the relative intensity of the complex ion is 0.5, we found that the porphyrin-calix[4]arene complex with the higher value of E1/2 corresponded to that with the larger association constant (Kass), as measured by 1H-NMR in CDCl 3. Both our ESI-MS and NMR studies proved that the number of hydrogen bonds and the rigidity of the calix[4]arene stabilized the complex. The ESI-MS technique could be successful in screening the binding affinity in host-guest systems with a small amount of sample.

Original languageEnglish
Pages (from-to)2065-2068
Number of pages4
JournalRapid Communications in Mass Spectrometry
Volume18
Issue number18
DOIs
Publication statusPublished - 2004

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Electrospray ionization
Porphyrins
Mass spectrometry
Nuclear magnetic resonance
Ions
Rigidity
Hydrogen bonds
Screening
Sodium
Association reactions
Decomposition
calix(4)arene

ASJC Scopus subject areas

  • Analytical Chemistry
  • Spectroscopy

Cite this

Stability of porphyrin-calix[4]arene complexes analyzed by electrospray ionization mass spectrometry. / Arai, Satoshi; Ishihara, Shinsuke; Takeoka, Shinji; Ohkawa, Haruki; Shibue, Toshimichi; Nishide, Hiroyuki.

In: Rapid Communications in Mass Spectrometry, Vol. 18, No. 18, 2004, p. 2065-2068.

Research output: Contribution to journalArticle

Arai, Satoshi ; Ishihara, Shinsuke ; Takeoka, Shinji ; Ohkawa, Haruki ; Shibue, Toshimichi ; Nishide, Hiroyuki. / Stability of porphyrin-calix[4]arene complexes analyzed by electrospray ionization mass spectrometry. In: Rapid Communications in Mass Spectrometry. 2004 ; Vol. 18, No. 18. pp. 2065-2068.
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AU - Nishide, Hiroyuki

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