Stand-alone micro fluidic system using partly disposable PDMS microwell array for high throughput cell analysis

Kasumi Miyamoto, Ryo Yamamoto, Kentaro Kawai, Shuichi Shoji

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    A stand-alone microfluidic system consists of a reusable flow control part and a disposable microwell array for high throughput cell analysis is proposed. The flow control part is realized with addressable microvalve array driven by compactly-fabricated solenoid actuators and EOF micropumps. Disposable 16 microwell array with 4 reagent injection ports was fabricated using a PDMS structure. The disposable fluidic chip can be easily replaced to different functional fluidic networks depended on their actual uses. The prototype system with 2×5 (52) on-chip hydraulic valves that are driven by 10 (25) solenoid actuators was fabricated. Precise reagent injection of ten-nanoliter order to each microwell was successfully carried out.

    Original languageEnglish
    Title of host publication2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
    Pages2944-2947
    Number of pages4
    DOIs
    Publication statusPublished - 2011
    Event2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11 - Beijing
    Duration: 2011 Jun 52011 Jun 9

    Other

    Other2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
    CityBeijing
    Period11/6/511/6/9

    Fingerprint

    Solenoids
    Fluidics
    Flow control
    Actuators
    Throughput
    Microfluidics
    Hydraulics

    Keywords

    • Access-tube-free
    • Addressable valve control system
    • Hydraulic valve
    • Partly disposable
    • Stand-alone

    ASJC Scopus subject areas

    • Hardware and Architecture
    • Electrical and Electronic Engineering

    Cite this

    Miyamoto, K., Yamamoto, R., Kawai, K., & Shoji, S. (2011). Stand-alone micro fluidic system using partly disposable PDMS microwell array for high throughput cell analysis. In 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11 (pp. 2944-2947). [5969418] https://doi.org/10.1109/TRANSDUCERS.2011.5969418

    Stand-alone micro fluidic system using partly disposable PDMS microwell array for high throughput cell analysis. / Miyamoto, Kasumi; Yamamoto, Ryo; Kawai, Kentaro; Shoji, Shuichi.

    2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11. 2011. p. 2944-2947 5969418.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Miyamoto, K, Yamamoto, R, Kawai, K & Shoji, S 2011, Stand-alone micro fluidic system using partly disposable PDMS microwell array for high throughput cell analysis. in 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11., 5969418, pp. 2944-2947, 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11, Beijing, 11/6/5. https://doi.org/10.1109/TRANSDUCERS.2011.5969418
    Miyamoto K, Yamamoto R, Kawai K, Shoji S. Stand-alone micro fluidic system using partly disposable PDMS microwell array for high throughput cell analysis. In 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11. 2011. p. 2944-2947. 5969418 https://doi.org/10.1109/TRANSDUCERS.2011.5969418
    Miyamoto, Kasumi ; Yamamoto, Ryo ; Kawai, Kentaro ; Shoji, Shuichi. / Stand-alone micro fluidic system using partly disposable PDMS microwell array for high throughput cell analysis. 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11. 2011. pp. 2944-2947
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