Stereoselective synthesis of allylsilanes bearing tetrasubstituted olefin via 2,2-Diborylethylsilane

Kohei Endo, Akira Sakamoto, Takahiro Ohkubo, Takanori Shibata

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    Abstract

    The regio-and stereoselective synthesis of allylsilane derivatives bearing a tetrasubstituted olefin was achieved using 2,2-diborylethylsilane as a key intermediate. The regioselective deprotonation of a 2,2-diborylethylsilane with LTMP and the subsequent nucleophilic addition to ketones gave corresponding allylsilanes in good to excellent yield with excellent stereoselectivity.

    Original languageEnglish
    Pages (from-to)1440-1442
    Number of pages3
    JournalChemistry Letters
    Volume40
    Issue number12
    DOIs
    Publication statusPublished - 2011

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    ASJC Scopus subject areas

    • Chemistry(all)

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