Stereoselective synthesis of allylsilanes bearing tetrasubstituted olefin via 2,2-Diborylethylsilane

Kohei Endo, Akira Sakamoto, Takahiro Ohkubo, Takanori Shibata

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

The regio-and stereoselective synthesis of allylsilane derivatives bearing a tetrasubstituted olefin was achieved using 2,2-diborylethylsilane as a key intermediate. The regioselective deprotonation of a 2,2-diborylethylsilane with LTMP and the subsequent nucleophilic addition to ketones gave corresponding allylsilanes in good to excellent yield with excellent stereoselectivity.

Original languageEnglish
Pages (from-to)1440-1442
Number of pages3
JournalChemistry Letters
Volume40
Issue number12
DOIs
Publication statusPublished - 2011

ASJC Scopus subject areas

  • Chemistry(all)

Fingerprint Dive into the research topics of 'Stereoselective synthesis of allylsilanes bearing tetrasubstituted olefin via 2,2-Diborylethylsilane'. Together they form a unique fingerprint.

  • Cite this