Stereospecific transformation of a chiral pyrimidyl alkanol into L-valine

Kenso Soai, Shigehisa Tanji, Yasutaka Kodaka, Takanori Shibata

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A chiral pyrimidyl alkanol with high enantiomeric excess is transformed into L-valine with high e.e. by a notable oxidative cleavage of pyrimidine ring using ruthenium oxide as a key step. This process would correlate natural α-amino acids with a chiral pyrimidyl alkanol, which is reported to possess an asymmetric autocatalytic activity with amplification of e.e.

Original languageEnglish
Pages (from-to)241-243
Number of pages3
JournalEnantiomer
Volume3
Issue number3
Publication statusPublished - 1998 Nov 24
Externally publishedYes

Keywords

  • Amino acid
  • Pyrimidyl alkanol
  • Stereospecific
  • Valine

ASJC Scopus subject areas

  • Chemistry(all)
  • Biochemistry
  • Biochemistry, Genetics and Molecular Biology(all)
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Stereospecific transformation of a chiral pyrimidyl alkanol into L-valine'. Together they form a unique fingerprint.

  • Cite this