Stretchable substrates using pneumatic actuators for monitoring mechanical-stress-dependent cell response

Yun Jung Heo, Eiji Iwase, Kiyoshi Matsumoto, Isao Shimoyama

Research output: Contribution to conferencePaper

1 Citation (Scopus)

Abstract

We present a stretchable substrate integrated with pneumatic actuators, designed to be able to supply mechanical stress to live cells on a microchip. The fabricated substrate shows areal strain of 2.49∼5.88% for input pressure of 5∼30psi. The fibroblasts plated on the present devices are stretched for the input pressure. Therefore, we experimentally verified that the fabricated stretchable substrates are able to culture and stretch the fibroblasts, showing potential applications for monitoring the mechanical-stress-dependent cell response.

Original languageEnglish
Pages579-581
Number of pages3
Publication statusPublished - 2008 Jan 1
Externally publishedYes
Event12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States
Duration: 2008 Oct 122008 Oct 16

Conference

Conference12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
CountryUnited States
CitySan Diego, CA
Period08/10/1208/10/16

Keywords

  • Mechanical stress
  • Pneumatic actuator
  • Stretchable substrate

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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  • Cite this

    Heo, Y. J., Iwase, E., Matsumoto, K., & Shimoyama, I. (2008). Stretchable substrates using pneumatic actuators for monitoring mechanical-stress-dependent cell response. 579-581. Paper presented at 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States.