Structural and functional analyses of proteins involved in translation, DNA recombination, chromosome architecture, and signal transduction

Hitoshi Kurumizaka, Shigeyuki Yokoyama

Research output: Contribution to journalArticle


Structural biology, in which the mechanisms of biological systems are elucidated by the three-dimensional structures of biomacromolecules, such as proteins and nucleic acids, is rapidly progressing. An aim of our research is to establish a novel strategy for understanding the functions of biomacromolecules through structural biology as well as biochemistry, molecular biology, and cell biology. In this article, we discuss our current progress in structural biology toward understanding the mechanisms of translation, DNA recombination, centromere architecture, and signal transduction.

Original languageEnglish
Pages (from-to)169-180
Number of pages12
JournalProgress in Biotechnology
Issue numberC
Publication statusPublished - 2002
Externally publishedYes


ASJC Scopus subject areas

  • Biotechnology

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