Studies on catalytic asymmetric Nozaki-Hiyama propargylation

Masahiro Inoue, Masahisa Nakada

    Research output: Contribution to journalArticle

    91 Citations (Scopus)

    Abstract

    (Equation Presented) Catalytic asymmetric Nozaki-Hiyama propargylation with ligand 1c proceeds with good to excellent enantioselectivity. Tuning of ligand 1 dramatically changes the enantioselectivity, and we propose models A and B to explain the change and outcome of the enantioselectivity.

    Original languageEnglish
    Pages (from-to)2977-2980
    Number of pages4
    JournalOrganic Letters
    Volume6
    Issue number17
    DOIs
    Publication statusPublished - 2004 Aug 19

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    Enantioselectivity
    Ligands
    ligands
    tuning
    Tuning

    ASJC Scopus subject areas

    • Molecular Medicine

    Cite this

    Studies on catalytic asymmetric Nozaki-Hiyama propargylation. / Inoue, Masahiro; Nakada, Masahisa.

    In: Organic Letters, Vol. 6, No. 17, 19.08.2004, p. 2977-2980.

    Research output: Contribution to journalArticle

    Inoue, Masahiro ; Nakada, Masahisa. / Studies on catalytic asymmetric Nozaki-Hiyama propargylation. In: Organic Letters. 2004 ; Vol. 6, No. 17. pp. 2977-2980.
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