Study of the effects of ionic liquids on lipid bilayers

Taylor T. Young; Stephen A. Sarles; Tianyu Wu; Matthew Green; Timothy Edward Long; Donald J. Leo

doi:10.1117/12.915078

Study of the effects of ionic liquids on lipid bilayers

Taylor T. Young, Stephen A. Sarles, Tianyu Wu, Matthew Green, Timothy Edward Long, Donald J. Leo

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

The formation of lipid bilayers between ionic liquid droplets is presented as a new means of forming functional bimolecular networks. Ionic liquids are molten salts that have a number of interesting properties, such as the ability to be a liquid at room temperature and exceedingly low vapor pressure. Our research demonstrates that it is possible to consistently and repeatable form lipid bilayers on droplets of ionic liquid solutions. Characterization of the bilayers interfaces shows that the ionic liquids have negligible effects on the stability and electrical properties of the bilayer. It is also shown that the conductance levels in the gating events of Alamethicin peptide are affected by some ionic liquids.

Original language	English
Title of host publication	Bioinspiration, Biomimetics, and Bioreplication 2012
Volume	8339
DOIs	https://doi.org/10.1117/12.915078
Publication status	Published - 2012 May 14
Externally published	Yes
Event	Bioinspiration, Biomimetics, and Bioreplication 2012 - San Diego, CA, United States Duration: 2012 Mar 12 → 2012 Mar 15

Other

Other	Bioinspiration, Biomimetics, and Bioreplication 2012
Country	United States
City	San Diego, CA
Period	12/3/12 → 12/3/15

Fingerprint

Keywords

Alamethicin
Droplet interface lipid bilayer
Ionic liquid
Regulated attachment method

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

Cite this

Young, T. T., Sarles, S. A., Wu, T., Green, M., Long, T. E., & Leo, D. J. (2012). Study of the effects of ionic liquids on lipid bilayers. In Bioinspiration, Biomimetics, and Bioreplication 2012 (Vol. 8339). [833906] https://doi.org/10.1117/12.915078

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abstract = "The formation of lipid bilayers between ionic liquid droplets is presented as a new means of forming functional bimolecular networks. Ionic liquids are molten salts that have a number of interesting properties, such as the ability to be a liquid at room temperature and exceedingly low vapor pressure. Our research demonstrates that it is possible to consistently and repeatable form lipid bilayers on droplets of ionic liquid solutions. Characterization of the bilayers interfaces shows that the ionic liquids have negligible effects on the stability and electrical properties of the bilayer. It is also shown that the conductance levels in the gating events of Alamethicin peptide are affected by some ionic liquids.",

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AU - Young, Taylor T.

AU - Sarles, Stephen A.

AU - Wu, Tianyu

AU - Green, Matthew

AU - Long, Timothy Edward

AU - Leo, Donald J.

PY - 2012/5/14

Y1 - 2012/5/14

N2 - The formation of lipid bilayers between ionic liquid droplets is presented as a new means of forming functional bimolecular networks. Ionic liquids are molten salts that have a number of interesting properties, such as the ability to be a liquid at room temperature and exceedingly low vapor pressure. Our research demonstrates that it is possible to consistently and repeatable form lipid bilayers on droplets of ionic liquid solutions. Characterization of the bilayers interfaces shows that the ionic liquids have negligible effects on the stability and electrical properties of the bilayer. It is also shown that the conductance levels in the gating events of Alamethicin peptide are affected by some ionic liquids.

AB - The formation of lipid bilayers between ionic liquid droplets is presented as a new means of forming functional bimolecular networks. Ionic liquids are molten salts that have a number of interesting properties, such as the ability to be a liquid at room temperature and exceedingly low vapor pressure. Our research demonstrates that it is possible to consistently and repeatable form lipid bilayers on droplets of ionic liquid solutions. Characterization of the bilayers interfaces shows that the ionic liquids have negligible effects on the stability and electrical properties of the bilayer. It is also shown that the conductance levels in the gating events of Alamethicin peptide are affected by some ionic liquids.

KW - Alamethicin

KW - Droplet interface lipid bilayer

KW - Ionic liquid

KW - Regulated attachment method

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DO - 10.1117/12.915078

M3 - Conference contribution

AN - SCOPUS:84860738824

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VL - 8339

BT - Bioinspiration, Biomimetics, and Bioreplication 2012

T2 - Bioinspiration, Biomimetics, and Bioreplication 2012

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Access to Document

10.1117/12.915078